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RRAS2 Antibody

ArtNr ABC-ASC11622
Hersteller Abcepta
Menge 100 ug
Kategorie
Typ Antibody Primary
Applikationen WB, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Rabbit
Isotype IgG
Citations Ehrhardt A, Ehrhardt GR, Guo X, et al. Ras and relatives--job sharing and networking keep an old family together. Exp. Hematol. 2002; 30:1089-106.
Lowe DG, Capon DJ, Delwart E, et al. Structure of the human and murine R-Ras genes, novel genes closely related to Ras proto-oncogenes. Cell 1987; 48:137-46
Drivas GT, Shih A, Coutavas E, et al. Characterization of four novel Ras-like genes expressed in a human teratocarcinoma cell line. Mol. Cell. Biol. 1990;10:1793-8.
Luo H, Hao X, Ge C, et al. TC21 promotes cell motility and metastasis by regulating the expression of E-cadherin and N-cadherin in hepatocellular carcinoma. Int. J. Oncol. 2010; 37:853-9
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Lieferbar
Manufacturer - Applications
RRAS2 antibody can be used for detection of RRAS2 by Western blot at 1 - 2 µg/mL.
Manufacturer - Category
Primary Antibodies; Cancer; Signal Transduction; Inflammation mediated by chemokine and cytokine signaling
Manufacturer - Targets
RRAS2; Two isoforms of RRAS2 exists as a result of alternative splicing event.
Storage Conditions
RRAS2 antibody can be stored at 4? for three months and -20?, stable for up to one year.
Bio Background
RRAS2 Antibody: Activating mutations and overexpression of classical Ras subfamily members (K-RAS, N-RAS and H-RAS) have been widely investigated as key events in the development of human cancers. The RRAS subfamily of Ras-related proteins includes RRAS1, RRAS2 (TC21) and RRAS3 (M-Ras) show overall amino acid identity with the classical Ras subfamily (H-Ras, K-Ras and N-Ras) of 55–60%. RRAS2 is a small GTPbinding protein of the Ras superfamily of GTPases. It might transduce growth inhibitory signals across the cell membrane, exerting its effect through an effector shared with the Ras proteins. RRAS2 has high oncogenic potential and overexpression/mutations have been reported in several tumor tissues and cell lines.
Clonality
Polyclonal
Gene Name
RRAS2
Reactivity
H, M
Calculated Molecular Weight
23400
Antigen Source
homo sapiens
Purification
RRAS2 Antibody is affinity chromatography purified via peptide column.
Antibody Form
Liquid
Application Notes
RRAS2 antibody can be used for detection of RRAS2 by Western blot at 1 - 2 µg/mL.
Positive Control
Jurkat Cell Lysate
Buffer
RRAS2 Antibody is supplied in PBS containing 0.02% sodium azide.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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