ULK2 Antibody

ArtNr	ABC-ASC11654
Hersteller	Abcepta
Menge	100 ug
Kategorie	Antibodies Cell Biology Cell Status Immunohistochemistry Western Blot ELISA Immunofluorescence Autophagy Primary Antibodies Immunostaining
Typ	Antibody Primary
Applikationen	WB, IF, ELISA, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Suzuki K, Kubota Y, Sekito T, et al. Hierarchy of Atg proteins in pre-autophagosomal structure organization. Genes to Cells 2007; 12:209–18. Lee EJ and Tournier C. The requirement of uncoordinated 51-like kinase 1 (ULK1) and ULK2 in the regulation of autophagy. Autophagy 2011; 7:689-95. Jung CH, Jun CB, Ro SH, et al. ULK-ATG13-FIP200 complexes mediate mTOR signaling to the autophagy machinery. Mol. Biol. Cell 2009; 20:1992-2003. Zhou X, Babu JR, da Silva S, et al.Unc-51-like kinase 1/2-mediated endocytic processes regulate filopodia extension and branching of sensory axons. Proc. Natl. Acad. Sci. USA 2007; 104:5842-7.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Lieferbar
Manufacturer - Applications	ULK2 Antibody can be used for detection of ULK2 by Western blot at 1 µg/mL.
Manufacturer - Category	Primary Antibodies; Signal Transduction; Autophagy; Regulation of autophagy
Manufacturer - Targets	ULK2; At least two isoforms of ULK2 are known to exist; this antibody will detect both isoforms. ULK2 antibody is predicted to not cross-react with ULK1.
Storage Conditions	ULK2 antibody can be stored at 4? for three months and -20?, stable for up to one year.
Bio Background	ULK2 Antibody: ULK2, also known as ATG1B, is a key serine/threonine protein kinase probably acting at the most upstream step of autophagosome formation. Knockout of ULK2 results in a severe defect in the autophagy pathway. ULK2 is highly conserved among eukaryotes and shows high homology with its related protein ULK1. Both ULK1 and ULK2 form a complex with ATG13 and FIP200 that mediates TOR signaling and is essential for autophagy. Like ULK1, ULK2 is also thought to be involved in early neuronal growth and differentiation.
Clonality	Polyclonal
Gene Name	ULK2
Reactivity	H
Calculated Molecular Weight	112694
Antigen Source	homo sapiens
Purification	ULK2 Antibody is affinity chromatography purified via peptide column.
Antibody Form	Liquid
Application Notes	ULK2 Antibody can be used for detection of ULK2 by Western blot at 1 µg/mL.
Positive Control	Human Brain Tissue Lysate
Buffer	ULK2 Antibody is supplied in PBS containing 0.02% sodium azide.

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Menge: 100 ug

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Lieferung vsl. bis 01.01.2026

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