AKT1S1 Antibody

AKT1S1 antibody can be used for detection of AKT1S1 by Western blot at 1 - 2 μ g/mL.

AKT1S1 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human AKT1S1.
The immunogen is located within amino acids 190 - 240 of AKT1S1.

AKT1S1 Antibody: The Akt signaling pathway contributes to the regulation of apoptosis after a variety of cell death signals. AKT1S1, also known as PRAS40, is a proline-rich substrate of the kinase AKT1 and is thought to play a role in neuroprotection mediated by nerve growth factor (NGF) after transient focal cerebral ischemia (1). AKT1S1 is also a substrate and potential regulator of mammalian target of rapamycin (mTOR), a serine/threonine kinase that regulates cell growth and cell cycle, and a negative regulator of autophagy (2). Treatment with the insulin-like growth factor-1 (IGF1) can indusce the phosphorylation of AKT1S1 via the PI3K/AKT signaling pathway in PC12 cells (3).

AKT1S1 {ECO:0000312|EMBL:AAH16043.1}

27383

AKT1S1 Antibody is affinity chromatography purified via peptide column.

AKT1S1 antibody can be used for detection of AKT1S1 by Western blot at 1 - 2 μ g/mL.

AKT1S1 Antibody is supplied in PBS containing 0.02% sodium azide.