HDAC1 Antibody

HDAC1; HDAC1 antibody is human, mouse and rat reactive. HDAC1 antibody is predicted to not cross-react with other members of the HDAC family.

The histone deacetylase (HDAC) family contains multiple members which are divided into four classes. Class I of the HDAC family comprises four members, HDAC1, 2, 3, and 8, each of which contains a deacetylase domain and exhibits a different, individual substrate specificity and function in vivo (1). HDAC1 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) (1, 2). HDAC1 gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events (3, 4).

HDAC1 {ECO:0000303|PubMed:10846170, ECO:0000312|HGNC:HGNC:4852}

55103

HDAC1 antibody is affinity chromatography purified via peptide column.

HDAC1 antibody can be used for detection of HDAC1 by Western blot at 1 - 2 µg/ml.

HDAC1 antibody is supplied in PBS containing 0.02% sodium azide.