DAF Antibody

ArtNr	ABC-ASC11840
Hersteller	Abcepta
Menge	100 ug
Kategorie	Neuroscience Neuroinflammation Antibodies Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies Immunostaining
Typ	Antibody Primary
Applikationen	WB, IF, ELISA, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Nicholson-Weller A, March JP, Rosen CE, et al. Surface membrane expression by human blood leukocytes and platelts of decay-accelerating factor, a regulatory protein of the complement system. Blood 1985; 65:1237-44. Seya T and Atkinson JP. Functional properties of membrane cofactor protein of complement. Biochem. J. 1989; 64:581-8. Storry JR, Reid ME, and Yazer MH. The Cromer blood group system: a review. Immunohematology 2010; 109-18.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
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Manufacturer - Category	Primary Antibodies; Immunology; Host cell receptor for virus entry; Viral entry into host cell; Host-virus interaction; Immunity; Innate immunity
Manufacturer - Targets	CD55; DAF antibody is human specific. At least two isoforms of DAF are known to exist; this antibody will only detect the longest isoform.
Storage Conditions	DAF antibody can be stored at 4? for three months and -20?, stable for up to one year.
Bio Background	The decay-accelerating factor (DAF), also known as CD55, is an integral membrane glycoprotein that is involved in the regulation of the complement cascade (1). DAF limits excessive complement activation by accelerating their decay following DAF binding, thereby disrupting the cascade and preventing damage to host cells (2). Antigens present on the DAF glycoprotein constitute the Cromer blood group system (CROM) (3).
Clonality	Polyclonal
Gene Name	CD55
Reactivity	H
Calculated Molecular Weight	41400
Antigen Source	homo sapiens
Purification	DAF antibody is affinity chromatography purified via peptide column.
Antibody Form	Liquid
Application Notes	DAF body can be used for detection of DAF by Western blot at 1 - 2 µg/ml. Antibody can also be used for Immunohistochemistry starting at 5 µg/mL. For immunofluorescence start at 20 µg/mL.
Positive Control	A549 Cell Lysate
Buffer	DAF antibody is supplied in PBS containing 0.02% sodium azide.

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ABC-ASC11840-datasheet.pdf

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Menge: 100 ug

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