Vergleich

RHOG Antibody

ArtNr ABC-ASC11858
Hersteller Abcepta
Menge 100 ug
Kategorie
Typ Antibody Primary
Applikationen WB, ELISA, IHC-P
Specific against other
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Lieferbar
Primary Accession
P84095
Application
WB, IHC-P, E
Bio Background
The ras homolog family member G (RHOG), also known as rho-related GTP-binding protein, is a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades (1). RHOG controls a pathway that requires the microtubule network and activates Rac1 and Cdc42Hs independently of their growth factor signaling pathway (2). RHOG is also involved in the transcriptional regulation of interferon-gamma and nuclear factor of activated T cells (NFAT) and the regulation of the actin skeleton in lymphocytes (3).
Bio References
Vincent S, Janteur P, and Fort P. Growth-regulated of rhoG, a new member of the ras homolog family. Mol. Cell Biol. 1992; 12:3138-48.
Gauthier-Rouviere C, Vignal E, Meriane M, et al. RhoG GTPase controls a pathway that independently activates Rac1 and Cdc42Hs. Mol. Biol. Cell 1998; 9:1379-94.
Vigorito E, Billadeu DD, Savoy D, et al. RhoG regulates gene expression and the actin skeleton in lymphocytes. Oncogene 2003; 22:330-42.
Clonality
Polyclonal
Gene ID
391
Gene Name
RHOG
Reactivity
H, M, Rat
Legend image 1
Western blot analysis of RHOG in human kidney tissue lysate with RHOG antibody at 1 µg/ml.
Type image 1
WB
Legend image 2
Immunohistochemistry of RHOG in mouse kidney tissue with RHOG antibody at 5 µg/ml.
Type image 2
IHC
Other Accession
NP_001656; 46249393
Isotype
IgG
Calculated MW
21309
Antigen Source
homo sapiens
Target/Specificity
RHOG; RHOG antibody is human, mouse and rat reactive.
Purification
RHOG antibody is affinity chromatography purified via peptide column.
Reconstitution & Storage
RHOG antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
Antibody Form
Liquid
Application Notes
RHOG antibody can be used for detection of RHOG by Western blot at 1 - 2 µg/ml. Antibody can also be used for immunohistochemistry starting at 5 µg/mL.
Positive Control
Human Kidney Tissue Lysate;
Buffer
RHOG antibody is supplied in PBS containing 0.02% sodium azide.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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