SOX4 Antibody

SOX4; SOX4 antibody is human, mouse and rat reactive.

SOX4 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate (1, 2). It may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin) (3). SOX4 contains one HMG box DNA-binding domain and may function in the apoptosis pathway leading to cell death. It has also been suggested to play a role in tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development (4, 5).

SOX4 {ECO:0000303|PubMed:8268656, ECO:0000312|HGNC:HGNC:11200}

47263

SOX4 antibody is affinity chromatography purified via peptide column.

SOX4 antibody can be used for detection of SOX4 by Western blot at 1 - 2 µg/mL. Antibody can also be used for immunohistochemistry starting at 5 µg/mL. For immunofluorescence start at 20 µg/mL.

SOX4 antibody is supplied in PBS containing 0.02% sodium azide.