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CCT2 Antibody (monoclonal) (M01)

CCT2 Antibody (monoclonal) (M01)

ArtNr	ABC-AT1427a
Hersteller	Abcepta
Menge	100 ug
Kategorie	Oncology Neuroscience Targets for Rodent Neurosciences Antibodies By Cell Type Western Blot ELISA Immunofluorescence Primary Antibodies Immunostaining
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, IF, ELISA
Clon	2G6
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Citations	1.Reconstitution of the human chaperonin CCT by co-expression of the eight distinct subunits in mammalian cells.Machida K, Masutani M, Kobayashi T, Mikami S, Nishino Y, Miyazawa A, Imataka H.Protein Expr Purif. 2011 Nov 22.2.BBS6, BBS10, and BBS12 form a complex with CCT/TRiC family chaperonins and mediate BBSome assembly.Seo S, Baye LM, Schulz NP, Beck JS, Zhang Q, Slusarski DC, Sheffield VC.Proc Natl Acad Sci U S A. 2010 Jan 4. [Epub ahead of print]
NCBI	NP_001185771.1,NP_006422.1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	T-complex protein 1 subunit beta,TCP-1-beta,CCT-beta,CCT2,99D81,CCTB
Similar products	CCT2, CCT-beta, CCTB, TCP-1-beta, T-complex protein 1 subunit beta, 99D81
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Manufacturer - Targets	CCT2 (NP_006422, 117 a.a. ~ 217 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of the gene described in this record have been observed but have not been thoroughly characterized.
Clonality	Monoclonal
Gene Name	CCT2
Subtitle	Mouse monoclonal antibody raised against a partial recombinant CCT2.
Reactivity	H
Antigen Source	Human: ~~ Positive
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution	IF WB: 1:500~1000 WB: 1:500~1000 E E
Org Accession	NP_006422
Gene Description	chaperonin containing TCP1, subunit 2 (beta)
Gene Summary	This gene encodes a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of the gene described in this record have been observed but have not been thoroughly characterized. [provided by RefSeq
Antigen Type	Recombinant Protein

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Menge: 100 ug

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