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CD81 Antibody (monoclonal) (M01)

ArtNr ABC-AT1446a
Hersteller Abcepta
Menge 100 ug
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen ELISA
Clon 2B7
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG1 Kappa
Citations Dengue hemorrhagic fever is associated with polymorphisms in JAK1. Silva LK, et al. Eur J Hum Genet, 2010 Jun 30. PMID 20588308.Claudin association with CD81 defines hepatitis C virus entry. Harris HJ, et al. J Biol Chem, 2010 Jul 2. PMID 20375010.Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus. Mosbruger TL, et al. J Infect Dis, 2010 May 1. PMID 20331378.New genetic associations detected in a host response study to hepatitis B vaccine. Davila S, et al. Genes Immun, 2010 Apr. PMID 20237496.CD81 gene defect in humans disrupts CD19 complex formation and leads to antibody deficiency. van Zelm MC, et al. J Clin Invest, 2010 Apr 1. PMID 20237408.
NCBI NP_004347.1
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias CD81 antigen,26 kDa cell surface protein TAPA-1,Target of the antiproliferative antibody 1,Tetraspanin-28,Tspan-28,CD81,CD81,TAPA1,TSPAN28
Similar products CD81, TAPA1, TSPAN28, 26 kDa cell surface protein TAPA-1, CD81 antigen, Tetraspanin-28, Tspan-28, Target of the antiproliferative antibody 1
Lieferbar
Manufacturer - Targets
CD81 (AAH02978, 25 a.a. ~ 127 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies.
Clonality
Monoclonal
Gene Name
CD81 {ECO:0000303|PubMed:8766544, ECO:0000312|HGNC:HGNC:1701}
Subtitle
Mouse monoclonal antibody raised against a partial recombinant CD81.
Reactivity
H
Antigen Source
Human: ~~ Positive
Formulation
Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Concentration
1mg/ml
Org Accession
AAH02978
Gene Description
CD81 molecule
Gene Summary
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. [provided by RefSeq
Antigen Type
Recombinant Protein

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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