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CTH Antibody (monoclonal) (M03)

CTH Antibody (monoclonal) (M03)

ArtNr	ABC-AT1668a
Hersteller	Abcepta
Menge	100 ug
Kategorie	Antibodies Immunohistochemistry Western Blot ELISA Primary Antibodies Immunostaining
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, IHC, ELISA
Clon	S51
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Mouse
Isotype	IgG1 Kappa
Citations	1.cGMP-Dependent Protein Kinase Contributes to Hydrogen Sulfide-Stimulated Vasorelaxation.Bucci M, Papapetropoulos A, Vellecco V, Zhou Z, Zaid A, Giannogonas P, Cantalupo A, Dhayade S, Karalis KP, Wang R, Feil R, Cirino G.PLoS One. 2012;7(12):e53319. doi: 10.1371/journal.pone.0053319. Epub 2012 Dec 28.2.Hydrogen sulfide impairs glucose utilization and increases gluconeogenesis in hepatocytes.Zhang L, Yang G, Untereiner A, Ju Y, Wu L, Wang R.Endocrinology. 2013 Jan;154(1):114-26. doi: 10.1210/en.2012-1658. Epub 2012 Nov 26.3.An investigation of the mechanisms of hydrogen sulfide-induced vasorelaxation in rat middle cerebral arteries.Streeter E, Hart J, Badoer E.Naunyn Schmiedebergs Arch Pharmacol. 2012 Jul 17.4.Characterization of Hydrogen Sulfide and Its Synthases, Cystathionine ?]-Synthase and Cystathionine ?^-Lyase, in Human Prostatic Tissue and Cells.Guo H, Gai JW, Wang Y, Jin HF, Du JB, Jin J.Urology. 2012 Feb;79(2):483.e1-5.5.Glucocorticoids suppress cystathionine gamma-lyase expression and H(2)S production in lipopolysaccharide-treated macrophages.Zhu XY, Liu SJ, Liu YJ, Wang S, Ni X.Cell Mol Life Sci. 2010 Jan 10. [Epub ahead of print]6.H2S contributes to the hepatic arterial buffer response and mediates vasorelaxation of the hepatic artery via activation of KATP channels.Siebert N, Cantre D, Eipel C, Vollmar B.Am J Physiol Gastrointest Liver Physiol. 2008 Dec;295(6):G1266-73. Epub 2008 Oct 30.
NCBI	NP_001177392.1,NP_001893.2,NP_714964.2
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Cystathionine gamma-lyase,Cysteine-protein sulfhydrase,Gamma-cystathionase,CTH
Similar products	CTH, Cystathionine gamma-lyase, Gamma-cystathionase, Cysteine-protein sulfhydrase
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Manufacturer - Targets	CTH (AAH15807, 1 a.a. ~ 405 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	This gene encodes a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in this gene cause cystathioninuria. Alternative splicing of this gene results in three transcript variants encoding different isoforms.
Clonality	Monoclonal
Gene Name	CTH
Subtitle	Mouse monoclonal antibody raised against a full length recombinant CTH.
Reactivity	H, M
Antigen Source	Human: ~~ Positive
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution	WB: 1:500~1000 WB: 1:500~1000 WB: 1:500~1000 WB: 1:500~1000 IHC
Org Accession	AAH15807
Gene Description	cystathionase (cystathionine gamma-lyase)
Gene Summary	This gene encodes a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in this gene cause cystathioninuria. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq
Antigen Type	Recombinant Protein

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ABC-AT1668a-datasheet.pdf

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Menge: 100 ug

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Lieferung vsl. bis 06.11.2025

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