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EGR1 Antibody (monoclonal) (M06)

EGR1 Antibody (monoclonal) (M06)

ArtNr	ABC-AT1865a
Hersteller	Abcepta
Menge	100 ug
Kategorie	Neuroscience Molecular Targets for Neuroscience Antibodies Western Blot ELISA Primary Antibodies Immunostaining
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, ELISA
Clon	3C7
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Citations	Cigarette smoke-induced Egr-1 represses T beta R-II expression in human skin dermal fibroblasts. Kim JN, et al. Toxicology, 2010 Sep 10. PMID 20621662.Advanced glycation end product (AGE)-receptor for AGE (RAGE) signaling and up-regulation of Egr-1 in hypoxic macrophages. Xu Y, et al. J Biol Chem, 2010 Jul 23. PMID 20507991.Placenta growth factor-induced early growth response 1 (Egr-1) regulates hypoxia-inducible factor-1alpha (HIF-1alpha) in endothelial cells. Patel N, et al. J Biol Chem, 2010 Jul 2. PMID 20448047.Mature human neutrophils constitutively express the transcription factor EGR-1. Cullen EM, et al. Mol Immunol, 2010 May. PMID 20363028.The effect of siRNA-Egr-1 and camptothecin on growth and chemosensitivity of breast cancer cell lines. Parra E, et al. Oncol Rep, 2010 Apr. PMID 20204305.
NCBI	NP_001955.1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Early growth response protein 1,EGR-1,AT225,Nerve growth factor-induced protein A,NGFI-A,Transcription factor ETR103,Transcription factor Zif268,Zinc finger protein 225,Zinc finger protein Krox-24,EGR1,KROX24,ZNF225
Similar products	EGR-1, EGR1, ZNF225, Zinc finger protein 225, AT225, NGFI-A, Early growth response protein 1, KROX24, Transcription factor ETR103, Nerve growth factor-induced protein A, Zinc finger protein Krox-24, Transcription factor Zif268
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Manufacturer - Targets	EGR1 (NP_001955, 444 a.a. ~ 543 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene.
Clonality	Monoclonal
Gene Name	EGR1
Subtitle	Mouse monoclonal antibody raised against a partial recombinant EGR1.
Reactivity	H
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Concentration	1 mg/ml
Dilution	WB: 1:500~1000 WB: 1:500~1000 E
Org Accession	NP_001955
Gene Description	early growth response 1
Gene Summary	The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene. [provided by RefSeq
Antigen Type	Recombinant Protein

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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ABC-AT1865a-datasheet.pdf

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Menge: 100 ug

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Lieferung vsl. bis 01.01.2026

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