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FASN Antibody (monoclonal) (M01)

FASN Antibody (monoclonal) (M01)

ArtNr	ABC-AT2002a
Hersteller	Abcepta
Menge	50 ug
Kategorie	Oncology Metabolism Cholesterol & Lipid Metabolism Antibodies By Cell Type Carcinoma Immunohistochemistry Immunoprecipitation Western Blot Immunofluorescence Enzymes Fatty Acid Synthesis Primary Antibodies
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, IF, IP, IHC
Clon	3F2-1F3
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Citations	1.Old proteins - new locations: myoglobin, haemoglobin, neuroglobin and cytoglobin in solid tumours and cancer cells.Gorr TA, Wichmann D, Pilarsky C, Theurillat JP, Fabrizius A, Laufs T, Bauer T, Koslowski M, Horn S, Burmester T, Hankeln T, Kristiansen G.Acta Physiol (Oxf). 2011 Jul;202(3):563-581.2.Endogenous myoglobin in human breast cancer is a hallmark of luminal cancer phenotype.Kristiansen G, Rose M, Geisler C, Fritzsche FR, Gerhardt J, Luke C, Ladhoff AM, Knuchel R, Dietel M, Moch H, Varga Z, Theurillat JP, Gorr TA, Dahl E.Br J Cancer. 2010 Jun 8;102(12):1736-45.
NCBI	NP_004095.4
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Similar products	FAS, FASN, Fatty acid synthase, [Acyl-carrier-protein] S-acetyltransferase, [Acyl-carrier-protein] S-malonyltransferase, 3-oxoacyl-[acyl-carrier-protein] synthase, 3-oxoacyl-[acyl-carrier-protein] reductase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase, Enoyl-[acyl-carrier-protein] reductase, Oleoyl-[acyl-carrier-protein] hydrolase
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Manufacturer - Targets	FASN (AAH07909, 1 a.a. ~ 439 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.
Clonality	Monoclonal
Gene Name	FASN
Subtitle	Mouse monoclonal antibody raised against a full length recombinant FASN.
Reactivity	H
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Concentration	1mg/ml
Dilution	IF IP WB: 1:500~1000 WB: 1:500~1000 WB: 1:500~1000
Org Accession	AAH07909
Gene Description	fatty acid synthase
Gene Summary	The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha. [provided by RefSeq
Antigen Type	Recombinant Protein
Manufacturer - Alias	Fatty acid synthase, [Acyl-carrier-protein] S-acetyltransferase, [Acyl-carrier-protein] S-malonyltransferase, 3-oxoacyl-[acyl-carrier-protein] synthase, 3-oxoacyl-[acyl-carrier-protein] reductase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase, Enoyl-[acyl-carrier-protein] reductase, Oleoyl-[acyl-carrier-protein] hydrolase, FASN, FAS
Manufacturer - Similar	Fatty acid synthase, [Acyl-carrier-protein] S-acetyltransferase, [Acyl-carrier-protein] S-malonyltransferase, 3-oxoacyl-[acyl-carrier-protein] synthase, 3-oxoacyl-[acyl-carrier-protein] reductase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase, Enoyl-[acyl-carrier-protein] reductase, Oleoyl-[acyl-carrier-protein] hydrolase, FASN, FAS

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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ABC-AT2002a-datasheet.pdf

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Menge: 50 ug

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Lieferung vsl. bis 01.01.2026

Express-Lieferung: 8 Tage sparen

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