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FXR1 Antibody (monoclonal) (M01)

FXR1 Antibody (monoclonal) (M01)

ArtNr	ABC-AT2127a
Hersteller	Abcepta
Menge	100 ug
Kategorie	Neuroscience Molecular Targets for Neuroscience Antibodies Immunohistochemistry Western Blot ELISA Primary Antibodies Immunostaining
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, IHC, ELISA
Clon	2G11
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Citations	Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. International Schizophrenia Consortium, et al. Nature, 2009 Aug 6. PMID 19571811.Discrimination of common and unique RNA-binding activities among Fragile X mental retardation protein paralogs. Darnell JC, et al. Hum Mol Genet, 2009 Sep 1. PMID 19487368.Alteration of expression of muscle specific isoforms of the fragile X related protein 1 (FXR1P) in facioscapulohumeral muscular dystrophy patients. Davidovic L, et al. J Med Genet, 2008 Oct. PMID 18628314.Toward a confocal subcellular atlas of the human proteome. Barbe L, et al. Mol Cell Proteomics, 2008 Mar. PMID 18029348.AU-rich-element-mediated upregulation of translation by FXR1 and Argonaute 2. Vasudevan S, et al. Cell, 2007 Mar 23. PMID 17382880.
NCBI	NP_001013456.1,NP_001013457.1,NP_005078.2
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Fragile X mental retardation syndrome-related protein 1,hFXR1p,FXR1
Similar products	FXR1, Fragile X mental retardation syndrome-related protein 1, hFXR1p
Lieferbar
Manufacturer - Targets	FXR1 (AAH28983, 121 a.a. ~ 220 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	The protein encoded by this gene is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene.
Clonality	Monoclonal
Gene Name	FXR1 {ECO:0000303\|PubMed:7781595, ECO:0000312\|HGNC:HGNC:4023}
Subtitle	Mouse monoclonal antibody raised against a partial recombinant FXR1.
Reactivity	H
Antigen Source	Human: ~~ Positive
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution	WB: 1:500~1000 WB: 1:500~1000 IHC E
Org Accession	AAH28983
Gene Description	fragile X mental retardation, autosomal homolog 1
Gene Summary	The protein encoded by this gene is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Antigen Type	Recombinant Protein

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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ABC-AT2127a-datasheet.pdf

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Menge: 100 ug

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