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G22P1 Antibody (monoclonal) (M01)

ArtNr ABC-AT2136a
Hersteller Abcepta
Menge 100 ug
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB, IF, IHC, ELISA
Clon 4C2-1A6
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG1 Kappa
Citations 1.DNA-PKcs Expression Predicts Response to Radiotherapy in Prostate Cancer.Bouchaert P, Guerif S, Debiais C, Irani J, Fromont G.Int J Radiat Oncol Biol Phys. 2012 Apr 10. [Epub ahead of print]2.Myonuclear breakdown in sporadic inclusion body myositis is accompanied by DNA double strand breaks.Nishii M, Nakano S, Nakamura S, Wate R, Shinde A, Kaneko S, Kusaka H.Neuromuscul Disord. 2011 Feb 23. [Epub ahead of print]
NCBI NP_001460.1
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Similar products Ku70, G22P1, XRCC6, 70 kDa subunit of Ku antigen, CTC75, CTCBF, DNA repair protein XRCC6, Lupus Ku autoantigen protein p70, TLAA, X-ray repair cross-complementing protein 6, 364-, Thyroid-lupus autoantigen, 5'-deoxyribose-5-phosphate lyase Ku70, 5'-dRP lyase Ku70, X-ray repair complementing defective repair in Chinese hamster cells 6, ATP-dependent DNA helicase 2 subunit 1, ATP-dependent DNA helicase II 70 kDa subunit, CTC box-binding factor 75 kDa subunit, 4299-
Lieferbar
Manufacturer - Targets
XRCC6 (AAH08343.1, 1 a.a. ~ 609 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
Clonality
Monoclonal
Gene Name
XRCC6
Subtitle
Mouse monoclonal antibody raised against a full length recombinant XRCC6.
Reactivity
H
Antigen Source
Human: ~~ Positive
Formulation
Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution
IF
WB: 1:500~1000
WB: 1:500~1000
WB: 1:500~1000
IHC
Org Accession
AAH08343.1
Gene Description
X-ray repair complementing defective repair in Chinese hamster cells 6
Gene Summary
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq
Antigen Type
Recombinant Protein
Manufacturer - Alias
X-ray repair cross-complementing protein 6, 364-, 4299-, 5'-deoxyribose-5-phosphate lyase Ku70, 5'-dRP lyase Ku70, 70 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 1, ATP-dependent DNA helicase II 70 kDa subunit, CTC box-binding factor 75 kDa subunit, CTC75, CTCBF, DNA repair protein XRCC6, Lupus Ku autoantigen protein p70, Ku70, Thyroid-lupus autoantigen, TLAA, X-ray repair complementing defective repair in Chinese hamster cells 6, XRCC6, G22P1
Manufacturer - Similar
X-ray repair cross-complementing protein 6, 364-, 4299-, 5'-deoxyribose-5-phosphate lyase Ku70, 5'-dRP lyase Ku70, 70 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 1, ATP-dependent DNA helicase II 70 kDa subunit, CTC box-binding factor 75 kDa subunit, CTC75, CTCBF, DNA repair protein XRCC6, Lupus Ku autoantigen protein p70, Ku70, Thyroid-lupus autoantigen, TLAA, X-ray repair complementing defective repair in Chinese hamster cells 6, XRCC6, G22P1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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