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GATA2 Antibody (monoclonal) (M01)

GATA2 Antibody (monoclonal) (M01)

ArtNr	ABC-AT2157a
Hersteller	Abcepta
Menge	100 ug
Kategorie	Neuroscience Neural Lineage Markers Antibodies Western Blot ELISA Immunofluorescence Primary Antibodies Immunostaining Cytoskeleton Markers
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, IF, ELISA
Clon	2D11
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2a Kappa
Citations	Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Acetylation of lysine 564 adjacent to the C-terminal binding protein-binding motif in EVI1 is crucial for transcriptional activation of GATA2. Shimahara A, et al. J Biol Chem, 2010 May 28. PMID 20363750.Discovering hematopoietic mechanisms through genome-wide analysis of GATA factor chromatin occupancy. Fujiwara T, et al. Mol Cell, 2009 Nov 25. PMID 19941826.Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Talmud PJ, et al. Am J Hum Genet, 2009 Nov. PMID 19913121.The transcription factor GATA-2 does not associate with angiographic coronary artery disease in the Ottawa Heart Genomics and Cleveland Clinic GeneBank Studies. Dandona S, et al. Hum Genet, 2010 Jan. PMID 19885677.
NCBI	NP_001139133.1,NP_001139134.1,NP_116027.2
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Endothelial transcription factor GATA-2,GATA-binding protein 2,GATA2
Similar products	GATA2, GATA-binding protein 2, Endothelial transcription factor GATA-2
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Manufacturer - Targets	GATA2 (AAH18988, 1 a.a. ~ 102 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	This gene encodes a member of the GATA family of zinc-finger transcription factors that are named for the consensus nucleotide sequence they bind in the promoter regions of target genes. The encoded protein plays an essential role in regulating transcription of genes involved in the development and proliferation of hematopoietic and endocrine cell lineages. Alternative splicing results in multiple transcript variants.
Clonality	Monoclonal
Gene Name	GATA2
Subtitle	Mouse monoclonal antibody raised against a partial recombinant GATA2.
Reactivity	H
Antigen Source	Human: ~~ Positive
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution	IF WB: 1:500~1000 WB: 1:500~1000 WB: 1:500~1000 WB: 1:500~1000
Org Accession	AAH18988
Gene Description	GATA binding protein 2
Gene Summary	This gene encodes a member of the GATA family of zinc-finger transcription factors that are named for the consensus nucleotide sequence they bind in the promoter regions of target genes. The encoded protein plays an essential role in regulating transcription of genes involved in the development and proliferation of hematopoietic and endocrine cell lineages. Alternative splicing results in multiple transcript variants
Antigen Type	Recombinant Protein

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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ABC-AT2157a-datasheet.pdf

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Menge: 100 ug

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Lieferung vsl. bis 01.01.2026

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