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HDAC7A Antibody (monoclonal) (M01)

HDAC7A Antibody (monoclonal) (M01)

ArtNr	ABC-AT2341a
Hersteller	Abcepta
Menge	100 ug
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Applikationen	WB
Clon	2B11-1C1
Specific against	other
Host	Mouse
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	HDAC7, HDAC7A, Histone deacetylase 7, Histone deacetylase 7A, HD7, HD7a
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Primary Accession	Q8WUI4
Antigen Type	Recombinant Protein
Application	WB
Bio Background	Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Bio References	1.HDAC7 and FoxA1 in estrogen-mediated repression of RPRM.Malik S, Jiang S, Garee JP, Verdin E, Lee AV, OMalley BW, Zhang M, Belaguli NS, Oesterreich S.Mol Cell Biol. 2010 Jan; 30(2):399-412. Epub 2009 Nov 16.
Clonality	Monoclonal
Gene ID	51564
Gene Name	HDAC7
Subtitle	Mouse monoclonal antibody raised against a full length recombinant HDAC7A.
Reactivity	H
Legend image 1	Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (56.1 KDa) .
Type image 1	WB
Dilution image 1	1:500~1000
Legend image 2	HDAC7A monoclonal antibody (M01), clone 2B11-1C1 Western Blot analysis of HDAC7A expression in K-562 ( (Cat # AT2341a )
Type image 2	WB
Dilution image 2	1:500~1000
Legend image 3	Western Blot analysis of HDAC7A expression in transfected 293T cell line by HDAC7A monoclonal antibody (M01), clone 2B11-1C1. Lane 1: HDAC7A transfected lysate(29.6 KDa). Lane 2: Non-transfected lysate.
Type image 3	WB
Dilution image 3	1:500~1000
Legend image 4	Detection limit for recombinant GST tagged HDAC7A is approximately 0.3ng/ml as a capture antibody.
Type image 4	E
Other Accession	BC006453
Isotype	IgG2b Kappa
Antigen Source	Human: ~~ Positive
Target/Specificity	HDAC7A (AAH06453.1, 1 a.a. ~ 276 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
NCBI Accession	NP_001091886.1; NP_056216.2
	Clone: 2B11-1C1
Org Accession	AAH06453.1
Gene Description	histone deacetylase 7
Gene Summary	Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

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Menge: 100 ug

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