HDAC8 Antibody (monoclonal) (M01)

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.

HDAC8 {ECO:0000303|PubMed:10926844, ECO:0000312|HGNC:HGNC:13315}

H

IF
WB: 1:500~1000
WB: 1:500~1000
WB: 1:500~1000
E

histone deacetylase 8

Recombinant Protein