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IL23R Antibody (monoclonal) (M01)

IL23R Antibody (monoclonal) (M01)

ArtNr	ABC-AT2517a
Hersteller	Abcepta
Menge	100 ug
Kategorie	Antibodies Cell Biology Cell Culture Cytokines Western Blot ELISA Primary Antibodies Immunostaining
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, ELISA
Clon	3D7
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2a Kappa
Citations	Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Toll-like receptor 9, NOD2 and IL23R gene polymorphisms influenced outcome in AML patients transplanted from HLA-identical sibling donors. Elmaagacli AH, et al. Bone Marrow Transplant, 2010 Jul 12. PMID 20622911.Genome-wide association studies identify IL23R-IL12RB2 and IL10 as Beh?et's disease susceptibility loci. Mizuki N, et al. Nat Genet, 2010 Aug. PMID 20622879.Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Beh?et's disease. Remmers EF, et al. Nat Genet, 2010 Aug. PMID 20622878.A nonsynonymous polymorphism in IL23R gene is associated with risk of gastric cancer in a Chinese population. Chen J, et al. Mol Carcinog, 2010 Oct. PMID 20607725.
NCBI	NP_653302.2
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Interleukin-23 receptor,IL-23 receptor,IL-23R,IL23R
Similar products	IL23R, Interleukin-23 receptor, IL-23R, IL-23 receptor
Lieferbar
Manufacturer - Targets	IL23R (NP_653302, 553 a.a. ~ 628 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner.
Clonality	Monoclonal
Gene Name	IL23R
Subtitle	Mouse monoclonal antibody raised against a partial recombinant IL23R.
Reactivity	H
Antigen Source	Human: ~~ Positive
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution	WB: 1:500~1000 WB: 1:500~1000 E
Org Accession	NP_653302
Gene Description	interleukin 23 receptor
Gene Summary	The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner. [provided by RefSeq
Antigen Type	Recombinant Protein

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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ABC-AT2517a-datasheet.pdf

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Menge: 100 ug

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