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ITGA9 Antibody (monoclonal) (M01)

ITGA9 Antibody (monoclonal) (M01)

ArtNr	ABC-AT2567a
Hersteller	Abcepta
Menge	100 ug
Kategorie	Neuroscience Neural Adhesion Molecules Antibodies Western Blot Primary Antibodies
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB
Clon	30000
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Citations	1.Notch-mediated induction of N-cadherin and ?9-integrin confers higher invasive phenotype on rhabdomyosarcoma cells.Masia A, Almazan-Moga A, Velasco P, Reventos J, Toran N, Sanchez de Toledo J, Roma J, Gallego S.Br J Cancer. 2012 Oct 9;107(8):1374-83. doi: 10.1038/bjc.2012.411. Epub 2012 Sep 13.2.Osteopontin Is an Activator of Human Adipose Tissue Macrophages and Directly Affects Adipocyte Function.Zeyda M, Gollinger K, Todoric J, Kiefer FW, Keck M, Aszmann O, Prager G, Zlabinger GJ, Petzelbauer P, Stulnig TM.Endocrinology. 2011 Apr 5. [Epub ahead of print]3.Thrombin cleaved osteopontin regulates hemopoietic stem and progenitor cell functions through interactions with {alpha}9{beta}1 and {alpha}4{beta}1 integrins.Grassinger J, Haylock DN, Storan MJ, Haines GO, Williams B, Whitty GA, Vinson AR, Be CL, Li S, Sorensen ES, Tam PP, Denhardt DT, Sheppard D, Choong PF, Nilsson SK.Blood. 2009 Jul 2;114(1):49-59. Epub 2009 May 5.4.An Interstitial Deletion at 3p21.3 Results in the Genetic Fusion of MLH1 and ITGA9 in a Lynch Syndrome Family.Meyer C, Brieger A, Plotz G, Weber N, Passmann S, Dingermann T, Zeuzem S, Trojan J, Marschalek R.Clin Cancer Res. 2009 Feb 1;15(3):762-9.
NCBI	NP_002198.2
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Integrin alpha-9,Integrin alpha-RLC,ITGA9
Similar products	ITGA9, Integrin alpha-9, Integrin alpha-RLC
Lieferbar
Manufacturer - Targets	ITGA9 (NP_002198, 785 a.a. ~ 886 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell and cell-matrix adhesion. The protein encoded by this gene, when bound to the beta 1 chain, forms an integrin that is a receptor for VCAM1, cytotactin and osteopontin. Expression of this gene has been found to be upregulated in small cell lung cancers.
Clonality	Monoclonal
Gene Name	ITGA9
Subtitle	Mouse monoclonal antibody raised against a partial recombinant ITGA9.
Reactivity	H
Antigen Source	Human: ~~ Positive
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution	WB: 1:500~1000 WB: 1:500~1000
Org Accession	NP_002198
Gene Description	integrin, alpha 9
Gene Summary	This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell and cell-matrix adhesion. The protein encoded by this gene, when bound to the beta 1 chain, forms an integrin that is a receptor for VCAM1, cytotactin and osteopontin. Expression of this gene has been found to be upregulated in small cell lung cancers. [provided by RefSeq
Antigen Type	Recombinant Protein

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ABC-AT2567a-datasheet.pdf

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Menge: 100 ug

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Lieferung vsl. bis 01.01.2026

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