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KRAS Antibody (monoclonal) (M02)

KRAS Antibody (monoclonal) (M02)

ArtNr	ABC-AT2651a
Hersteller	Abcepta
Menge	100 ug
Kategorie	Oncology Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Adenocarcinoma Cytoskeleton Western Blot ELISA Primary Antibodies By Organ Lung Cancer Colorectal Cancer Immunostaining small GTPases Ras Subfamily
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, ELISA
Clon	4F3
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2a Kappa
Citations	1.Synergistic Effects of Combined Wnt/KRAS Inhibition in Colorectal Cancer Cells.Mologni L, Brussolo S, Ceccon M, Gambacorti-Passerini C.PLoS One. 2012;7(12):e51449. doi: 10.1371/journal.pone.0051449. Epub 2012 Dec 5.
NCBI	NP_004976.2,NP_203524.1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	GTPase KRas,K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras,GTPase KRas,N-terminally processed,KRAS,KRAS2,RASK2
Similar products	KRAS, N-terminally processed, KRAS2, RASK2, GTPase KRas, K-Ras 2, Ki-Ras, c-K-ras, c-Ki-ras
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Manufacturer - Targets	KRAS (NP_004976, 16 a.a. ~ 125 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region.
Clonality	Monoclonal
Gene Name	KRAS
Subtitle	Mouse monoclonal antibody raised against a partial recombinant KRAS.
Reactivity	H
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Concentration	1 mg/ml
Dilution	WB: 1:500~1000 WB: 1:500~1000 WB: 1:500~1000 E
Org Accession	NP_004976
Gene Description	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
Gene Summary	This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq
Antigen Type	Recombinant Protein

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 ug

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