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MAPK13 Antibody (monoclonal) (M05)

MAPK13 Antibody (monoclonal) (M05)

ArtNr	ABC-AT2788a
Hersteller	Abcepta
Menge	100 ug
Kategorie	Oncology Neuroscience Neural Signaling Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Lymphoma Myeloma Melanoma Sarcoma Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies Immunostaining
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, IF, IHC, ELISA
Clon	2B2
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Citations	Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Human p38 delta MAP kinase mediates UV irradiation induced up-regulation of the gene expression of chemokine BRAK/CXCL14. Ozawa S, et al. Biochem Biophys Res Commun, 2010 Jun 11. PMID 20478268.p38delta mitogen-activated protein kinase regulates skin homeostasis and tumorigenesis. Efimova T. Cell Cycle, 2010 Feb 1. PMID 20090411.Polymorphisms in innate immunity genes and patients response to dendritic cell-based HIV immuno-treatment. Segat L, et al. Vaccine, 2010 Mar 2. PMID 20056178.Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Talmud PJ, et al. Am J Hum Genet, 2009 Nov. PMID 19913121.
NCBI	NP_002745.1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Mitogen-activated protein kinase 13,MAP kinase 13,MAPK 13,Mitogen-activated protein kinase p38 delta,MAP kinase p38 delta,Stress-activated protein kinase 4,MAPK13,PRKM13,SAPK4
Similar products	MAPK13, Mitogen-activated protein kinase 13, Mitogen-activated protein kinase p38 delta, Stress-activated protein kinase 4, SAPK4, PRKM13, MAP kinase 13, MAP kinase p38 delta, MAPK 13
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Manufacturer - Targets	MAPK13 (AAH00433, 251 a.a. ~ 365 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and cellular stress. MAP kinase kinases 3, and 6 can phosphorylate and activate this kinase. Transcription factor ATF2, and microtubule dynamics regulator stathmin have been shown to be the substrates of this kinase.
Clonality	Monoclonal
Gene Name	MAPK13
Subtitle	Mouse monoclonal antibody raised against a partial recombinant MAPK13.
Reactivity	H
Antigen Source	Human: ~~ Positive
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution	IF WB: 1:500~1000 WB: 1:500~1000 IHC E
Org Accession	AAH00433
Gene Description	mitogen-activated protein kinase 13
Gene Summary	The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and cellular stress. MAP kinase kinases 3, and 6 can phosphorylate and activate this kinase. Transcription factor ATF2, and microtubule dynamics regulator stathmin have been shown to be the substrates of this kinase. [provided by RefSeq
Antigen Type	Recombinant Protein

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Menge: 100 ug

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