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MMP28 Antibody (monoclonal) (M01)

MMP28 Antibody (monoclonal) (M01)

ArtNr	ABC-AT2882a
Hersteller	Abcepta
Menge	100 ug
Kategorie	Oncology Neuroscience Neuroinflammation Aging & Neurological Disorders Antibodies By Cell Type Blastoma Western Blot ELISA Primary Antibodies Immunostaining
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, ELISA
Clon	3C11
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2a Kappa
Citations	MMP28 gene expression is regulated by Sp1 transcription factor acetylation. Swingler TE, et al. Biochem J, 2010 Apr 14. PMID 20144149.Matrix metalloproteinase 28, a novel matrix metalloproteinase, is constitutively expressed in human intervertebral disc tissue and is present in matrix of more degenerated discs. Gruber HE, et al. Arthritis Res Ther, 2009. PMID 20003223.Expression of MMP-10, MMP-21, MMP-26, and MMP-28 in Merkel cell carcinoma. Suomela S, et al. Virchows Arch, 2009 Dec. PMID 19921252.Epilysin (MMP-28) is deposited to the basolateral extracellular matrix of epithelial cells. Heiskanen TJ, et al. Matrix Biol, 2009 Mar. PMID 19379669.Expression and function of matrix metalloproteinase (MMP)-28. Rodgers UR, et al. Matrix Biol, 2009 Jun. PMID 19375502.
NCBI	NP_001027449.1,NP_077278.1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Matrix metalloproteinase-28,MMP-28,3424-,Epilysin,MMP28,MMP25
Similar products	MMP25, MMP28, Matrix metalloproteinase-28, Epilysin, MMP-28, 3424-
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Manufacturer - Targets	MMP28 (NP_077278, 441 a.a. ~ 520 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix for both normal physiological processes, such as embryonic development, reproduction and tissue remodeling, and disease processes, such as asthma and metastasis. This gene encodes a secreted enzyme that degrades casein. Its expression pattern suggests that it plays a role in tissue homeostasis and in wound repair. Transcript variants encoding different isoforms have been described.
Clonality	Monoclonal
Gene Name	MMP28
Subtitle	Mouse monoclonal antibody raised against a partial recombinant MMP28.
Reactivity	H
Antigen Source	Human: ~~ Positive
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution	WB: 1:500~1000 E
Org Accession	NP_077278
Gene Description	matrix metallopeptidase 28
Gene Summary	Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix for both normal physiological processes, such as embryonic development, reproduction and tissue remodeling, and disease processes, such as asthma and metastasis. This gene encodes a secreted enzyme that degrades casein. Its expression pattern suggests that it plays a role in tissue homeostasis and in wound repair. Transcript variants encoding different isoforms have been described. [provided by RefSeq
Antigen Type	Recombinant Protein

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Menge: 100 ug

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