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MSI1 Antibody (monoclonal) (M05)

MSI1 Antibody (monoclonal) (M05)

ArtNr	ABC-AT2914a
Hersteller	Abcepta
Menge	100 ug
Kategorie	Oncology Neuroscience Neural Lineage Markers Antibodies By Cell Type Carcinoma Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies Immunostaining Adhesion Molecule Markers
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, IF, IHC, ELISA
Clon	1B11
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2b Kappa
Citations	Expression of putative stem cell genes Musashi-1 and beta1-integrin in human colorectal adenomas and adenocarcinomas. Fan LF, et al. Int J Colorectal Dis, 2010 Jan. PMID 19714342.Genomic analyses of musashi1 downstream targets show a strong association with cancer-related processes. de Sousa Abreu R, et al. J Biol Chem, 2009 May 1. PMID 19258308.Musashi-1 suppresses expression of Paneth cell-specific genes in human intestinal epithelial cells. Murayama M, et al. J Gastroenterol, 2009. PMID 19214660.Musashi1 modulates cell proliferation genes in the medulloblastoma cell line Daoy. Sanchez-Diaz PC, et al. BMC Cancer, 2008 Sep 30. PMID 18826648.Increased expression of the adult stem cell marker Musashi-1 in endometriosis and endometrial carcinoma. G?tte M, et al. J Pathol, 2008 Jul. PMID 18473332.
NCBI	NP_002433.1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	RNA-binding protein Musashi homolog 1,Musashi-1,MSI1
Similar products	MSI1, RNA-binding protein Musashi homolog 1, Musashi-1
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Manufacturer - Targets	MSI1 (NP_002433, 1 a.a. ~ 87 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	This gene encodes a protein containing two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. Expression of this gene has been correlated with the grade of the malignancy and proliferative activity in gliomas and melanomas. A pseudogene for this gene is located on chromosome 11q13.
Clonality	Monoclonal
Gene Name	MSI1
Subtitle	Mouse monoclonal antibody raised against a full length recombinant MSI1.
Reactivity	H
Antigen Source	Human: ~~ Positive
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution	IF WB: 1:500~1000 IHC E
Org Accession	NP_002433
Gene Description	musashi homolog 1 (Drosophila)
Gene Summary	This gene encodes a protein containing two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. Expression of this gene has been correlated with the grade of the malignancy and proliferative activity in gliomas and melanomas. A pseudogene for this gene is located on chromosome 11q13. [provided by RefSeq
Antigen Type	Recombinant Protein

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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ABC-AT2914a-datasheet.pdf

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