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NDRG1 Antibody (monoclonal) (M03)

ArtNr ABC-AT2991a
Hersteller Abcepta
Menge 100 ug
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB, IF, IHC, ELISA
Clon 2D7
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG2a Kappa
Citations 1.A novel molecular marker for early detection and evaluating prognosis of gastric cancer: N-myc downstream regulated gene-1 (NDRG1).Jiang K, Shen Z, Ye Y, Yang X, Wang S.Scand J Gastroenterol. 2010 Apr 14. [Epub ahead of print]2.Metastasis-related plasma membrane proteins of human breast cancer cells identified by comparative quantitative mass spectrometry.Leth-Larsen R, Lund R, Hansen HV, Laenkholm AV, Tarin D, Jensen ON, Ditzel HJ.Mol Cell Proteomics. 2009 Jun;8(6):1436-49. Epub 2009 Mar 24.
NCBI NP_001128714.1,NP_001245361.1,NP_001245362.1,NP_006087.2
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Protein NDRG1,Differentiation-related gene 1 protein,DRG-1,N-myc downstream-regulated gene 1 protein,Nickel-specific induction protein Cap43,Reducing agents and tunicamycin-responsive protein,RTP,Rit42,NDRG1,CAP43,DRG1,RTP
Similar products NDRG1, DRG1, CAP43, RTP, DRG-1, Protein NDRG1, Differentiation-related gene 1 protein, N-myc downstream-regulated gene 1 protein, Nickel-specific induction protein Cap43, Reducing agents and tunicamycin-responsive protein, Rit42
Lieferbar
Manufacturer - Targets
NDRG1 (AAH03175, 1 a.a. ~ 394 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background
This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. It is necessary for p53-mediated caspase activation and apoptosis. Mutation in this gene has been reported to be causative for hereditary motor and sensory neuropathy-Lom. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Clonality
Monoclonal
Gene Name
NDRG1
Subtitle
Mouse monoclonal antibody raised against a full length recombinant NDRG1.
Reactivity
H
Antigen Source
Human: ~~ Positive
Formulation
Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Concentration
0.5mg/ml
Dilution
IF
WB: 1:500~1000
IHC
E
Org Accession
AAH03175
Gene Description
N-myc downstream regulated 1
Gene Summary
This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. It is necessary for p53-mediated caspase activation and apoptosis. Mutation in this gene has been reported to be causative for hereditary motor and sensory neuropathy-Lom. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq
Antigen Type
Recombinant Protein

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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