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NPPB Antibody (monoclonal) (M01)

NPPB Antibody (monoclonal) (M01)

ArtNr	ABC-AT3086a
Hersteller	Abcepta
Menge	100 ug
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Applikationen	WB, IP
Clon	2D11
Specific against	other
Host	Mouse
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	NPPB, BNP-32, Brain natriuretic peptide 32, Natriuretic peptides B, Gamma-brain natriuretic peptide, BNP(1-32), BNP(5-29), BNP(1-30), BNP(1-29), BNP(1-28), BNP(2-31), BNP(3-32), BNP(3-30), BNP(3-29), BNP(4-32), BNP(4-31), BNP(4-30), BNP(4-29), BNP(4-27), BNP(5-32), BNP(5-31)
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Primary Accession	P16860
Antigen Type	Recombinant Protein
Application	WB, IP
Bio Background	This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis.
Bio References	1.The arrhythmogenic effect of self-assembling nanopeptide hydrogel scaffolds on neonatal mouse cardiomyocytes.Chiu YW, Chen WP, Su CC, Lee YC, Hsieh PH, Ho YLNanomedicine. 2014 Jan 31. pii: S1549-9634(14)00029-X. doi: 10.1016/j.nano.2014.01.005.
Clonality	Monoclonal
Gene ID	4879
Gene Name	NPPB
Subtitle	Mouse monoclonal antibody raised against a full length recombinant NPPB.
Reactivity	H
Legend image 1	Immunoprecipitation of NPPB transfected lysate using anti-NPPB monoclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with NPPB MaxPab rabbit polyclonal antibody.
Type image 1	IP
Legend image 2	Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (40.48 KDa) .
Type image 2	WB
Dilution image 2	1:500~1000
Legend image 3	Western Blot analysis of NPPB expression in transfected 293T cell line by NPPB monoclonal antibody (M01), clone 2D11. Lane 1: NPPB transfected lysate(14.726 KDa). Lane 2: Non-transfected lysate.
Type image 3	WB
Dilution image 3	1:500~1000
Other Accession	BC025785
Isotype	IgG3 Kappa
Antigen Source	Human: ~~ Positive
Target/Specificity	NPPB (AAH25785, 1 a.a. ~ 134 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
NCBI Accession	NP_002512.1
	Clone: 2D11
Org Accession	AAH25785
Gene Description	natriuretic peptide precursor B
Gene Summary	This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein' s biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq

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Menge: 100 ug

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Lieferung vsl. bis 06.11.2025

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