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NUDC Antibody (monoclonal) (M01)

NUDC Antibody (monoclonal) (M01)

ArtNr	ABC-AT3125a
Hersteller	Abcepta
Menge	100 ug
Kategorie	Neuroscience Neural Lineage Markers Antibodies Western Blot ELISA Immunofluorescence Primary Antibodies Immunostaining Neuronal Cell Markers
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, IF, ELISA
Clon	5G12
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Citations	Defining the human deubiquitinating enzyme interaction landscape. Sowa ME, et al. Cell, 2009 Jul 23. PMID 19615732.Interference RNA (RNAi)-based silencing of endogenous thrombopoietin receptor (Mpl) in Dami cells resulted in decreased hNUDC-mediated megakaryocyte proliferation and differentiation. Pang SF, et al. Exp Cell Res, 2009 Dec 10. PMID 19560457.hNUDC promotes the cell proliferation and differentiation in a leukemic cell line via activation of the thrombopoietin receptor (Mpl). Tang YS, et al. Leukemia, 2008 May. PMID 18288130.Regulation of cell differentiation by hNUDC via a Mpl-dependent mechanism in NIH 3T3 cells. Zhang YP, et al. Exp Cell Res, 2007 Sep 10. PMID 17658515.Large-scale mapping of human protein-protein interactions by mass spectrometry. Ewing RM, et al. Mol Syst Biol, 2007. PMID 17353931.
NCBI	NP_006591.1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Nuclear migration protein nudC,Nuclear distribution protein C homolog,NUDC
Similar products	NUDC, Nuclear migration protein nudC, Nuclear distribution protein C homolog
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Manufacturer - Targets	NUDC (AAH02399, 1 a.a. ~ 331 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	NudC was first identified as a regulator of nuclear movement in the asexual reproductive cycle of the filamentous fungus Aspergillus nidulans. Human NUDC is a nuclear movement protein that associates with dynein (see DYNC1H1; MIM 600112) (Aumais et al., 2003 [PubMed 12679384]).
Clonality	Monoclonal
Gene Name	NUDC
Subtitle	Mouse monoclonal antibody raised against a full length recombinant NUDC.
Reactivity	H
Antigen Source	Human: ~~ Positive
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution	IF WB: 1:500~1000 WB: 1:500~1000 E
Org Accession	AAH02399
Gene Description	nuclear distribution gene C homolog (A. nidulans)
Gene Summary	NudC was first identified as a regulator of nuclear movement in the asexual reproductive cycle of the filamentous fungus Aspergillus nidulans. Human NUDC is a nuclear movement protein that associates with dynein (see DYNC1H1; MIM 600112) (Aumais et al., 2003 [PubMed 12679384]).[supplied by OMIM
Antigen Type	Recombinant Protein

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ABC-AT3125a-datasheet.pdf

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Menge: 100 ug

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