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RAB27A Antibody (monoclonal) (M02)

RAB27A Antibody (monoclonal) (M02)

ArtNr	ABC-AT3518a
Hersteller	Abcepta
Menge	100 ug
Kategorie	Antibodies Cell Biology Cytoskeleton Immunohistochemistry Western Blot ELISA Primary Antibodies Immunostaining small GTPases Rab Subfamily
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, IHC, ELISA
Clon	1G7
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Citations	1.Activated Cdc42-Bound IQGAP1 Determines the Cellular Endocytic Site.Kimura T, Yamaoka M, Taniguchi S, Okamoto M, Takei M, Ando T, Iwamatsu A, Watanabe T, Kaibuchi K, Ishizaki T, Niki IMol Cell Biol. 2013 Dec;33(24):4834-43. doi: 10.1128/MCB.00895-13. Epub 2013 Oct 7.2.Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET.Peinado H, Aleckovic M, Lavotshkin S, Matei I, Costa-Silva B, Moreno-Bueno G, Hergueta-Redondo M, Williams C, Garcia-Santos G, Ghajar CM, Nitadori-Hoshino A, Hoffman C, Badal K, Garcia BA, Callahan MK, Yuan J, Martins VR, Skog J, Kaplan RN, Brady MS, Wolchok JD, Chapman PB, Kang Y, Bromberg J, Lyden D.Nat Med. 2012 May 27. doi: 10.1038/nm.2753.3.Stepwise Maturation of Lytic Granules during Differentiation and Activation of Human CD8+ T Lymphocytes.Sanchez-Ruiz Y, Valitutti S, Dupre L.PLoS One. 2011;6(11):e27057. Epub 2011 Nov 4.4.Synaptotagmin-like protein 1 interacts with the GTPase-activating protein Rap1GAP2 and regulates dense granule secretion in platelets.Neumuller O, Hoffmeister M, Babica J, Prelle C, Gegenbauer K, Smolenski AP.Blood. 2009 Aug 13;114(7):1396-404. Epub 2009 Jun 15.5.The GDP-dependent Rab27a effector coronin 3 controls endocytosis of secretory membrane in insulin-secreting cell lines.Kimura T, Kaneko Y, Yamada S, Ishihara H, Senda T, Iwamatsu A, Niki I.J Cell Sci. 2008 Sep 15;121(Pt 18):3092-8.
NCBI	NP_004571.2,NP_899057.1,NP_899058.1,NP_899059.1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Ras-related protein Rab-27A,Rab-27,GTP-binding protein Ram,RAB27A,RAB27
Similar products	RAB27A, RAB27, Ras-related protein Rab-27A, GTP-binding protein Ram, Rab-27
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Manufacturer - Targets	RAB27A (NP_004571, 122 a.a. ~ 221 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.
Clonality	Monoclonal
Gene Name	RAB27A
Subtitle	Mouse monoclonal antibody raised against a partial recombinant RAB27A.
Reactivity	H
Antigen Source	Human: ~~ Positive
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution	WB: 1:500~1000 WB: 1:500~1000 WB: 1:500~1000 WB: 1:500~1000 IHC
Org Accession	NP_004571
Gene Description	RAB27A, member RAS oncogene family
Gene Summary	The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. [provided by RefSeq
Antigen Type	Recombinant Protein

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Menge: 100 ug

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