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RAP2B Antibody (monoclonal) (M01)

RAP2B Antibody (monoclonal) (M01)

ArtNr	ABC-AT3564a
Hersteller	Abcepta
Menge	100 ug
Kategorie	Antibodies Cell Biology Cytoskeleton Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies small GTPases Ras Subfamily Rap Subfamily
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, IF, IHC
Clon	4F12-3C6
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2b Kappa
Citations	Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Proteome analysis of the thalamus and cerebrospinal fluid reveals glycolysis dysfunction and potential biomarkers candidates for schizophrenia. Martins-de-Souza D, et al. J Psychiatr Res, 2010 May 14. PMID 20471030.Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Talmud PJ, et al. Am J Hum Genet, 2009 Nov. PMID 19913121.Targeting of the small GTPase Rap2b, but not Rap1b, to lipid rafts is promoted by palmitoylation at Cys176 and Cys177 and is required for efficient protein activation in human platelets. Canobbio I, et al. Cell Signal, 2008 Sep. PMID 18582561.Identification of genes differentially expressed in human primary lung squamous cell carcinoma. Liu Y, et al. Lung Cancer, 2007 Jun. PMID 17316888.
NCBI	NP_002877.2
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Ras-related protein Rap-2b,RAP2B
Similar products	RAP2B, Ras-related protein Rap-2b
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Manufacturer - Targets	RAP2B (AAH12362, 1 a.a. ~ 183 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	This intronless gene belongs to a family of RAS-related genes. The proteins encoded by these genes share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between the RAP and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. Evidence suggests that this protein may be polyisoprenylated and palmitoylated.
Clonality	Monoclonal
Gene Name	RAP2B
Subtitle	Mouse monoclonal antibody raised against a full length recombinant RAP2B.
Reactivity	H
Antigen Source	Human: ~~ Positive
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution	IF WB: 1:500~1000 WB: 1:500~1000 IHC
Org Accession	AAH12362
Gene Description	RAP2B, member of RAS oncogene family
Gene Summary	This intronless gene belongs to a family of RAS-related genes. The proteins encoded by these genes share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between the RAP and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. Evidence suggests that this protein may be polyisoprenylated and palmitoylated. [provided by RefSeq
Antigen Type	Recombinant Protein

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ABC-AT3564a-datasheet.pdf

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Menge: 100 ug

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