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RUNX1 Antibody (monoclonal) (M06)

ArtNr ABC-AT3739a
Hersteller Abcepta
Menge 100 ug
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB, IF, IHC, ELISA
Clon 2C10
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG2a Kappa
Citations 1.Transcription factor Runx2 is a regulator of epithelial-mesenchymal transition and invasion in thyroid carcinomas.Niu DF, Kondo T, Nakazawa T, Oishi N, Kawasaki T, Mochizuki K, Yamane T, Katoh R.Lab Invest. 2012 May 28. doi: 10.1038/labinvest.2012.84.2.Megakaryocytic expression of miRNA 10a, 17-5p, 20a and 126 in Philadelphia chromosome-negative myeloproliferative neoplasm.Hussein K, Dralle W, Theophile K, Kreipe H, Bock O.Ann Hematol. 2009 Apr;88(4):325-32. Epub 2008 Sep 5.
NCBI NP_001001890.1,NP_001116079.1,NP_001745.2
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Similar products RUNX1, AML1, CBFA2, Acute myeloid leukemia 1 protein, Runt-related transcription factor 1, Core-binding factor subunit alpha-2, CBF-alpha-2, Oncogene AML-1, Polyomavirus enhancer-binding protein 2 alpha B subunit, PEA2-alpha B, PEBP2-alpha B, SL3-3 enhancer factor 1 alpha B subunit, SL3/AKV core-binding factor alpha B subunit
Lieferbar
Manufacturer - Targets
RUNX1 (NP_001001890.1, 210 a.a. ~ 310 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background
Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene.
Clonality
Monoclonal
Gene Name
RUNX1
Subtitle
Mouse monoclonal antibody raised against a partial recombinant RUNX1.
Reactivity
H
Antigen Source
Human: ~~ Positive
Formulation
Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution
IF
WB: 1:500~1000
WB: 1:500~1000
IHC
E
Org Accession
NP_001001890.1
Gene Description
runt-related transcription factor 1
Gene Summary
Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Antigen Type
Recombinant Protein
Manufacturer - Alias
Runt-related transcription factor 1, Acute myeloid leukemia 1 protein, Core-binding factor subunit alpha-2, CBF-alpha-2, Oncogene AML-1, Polyomavirus enhancer-binding protein 2 alpha B subunit, PEA2-alpha B, PEBP2-alpha B, SL3-3 enhancer factor 1 alpha B subunit, SL3/AKV core-binding factor alpha B subunit, RUNX1, AML1, CBFA2
Manufacturer - Similar
Runt-related transcription factor 1, Acute myeloid leukemia 1 protein, Core-binding factor subunit alpha-2, CBF-alpha-2, Oncogene AML-1, Polyomavirus enhancer-binding protein 2 alpha B subunit, PEA2-alpha B, PEBP2-alpha B, SL3-3 enhancer factor 1 alpha B subunit, SL3/AKV core-binding factor alpha B subunit, RUNX1, AML1, CBFA2

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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