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SCN9A Antibody (monoclonal) (M01)

SCN9A Antibody (monoclonal) (M01)

ArtNr	ABC-AT3795a
Hersteller	Abcepta
Menge	100 ug
Kategorie	Neuroscience Molecular Targets for Neuroscience Neural Adhesion Molecules Antibodies Western Blot Primary Antibodies
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB
Clon	5A11
Specific against	Human (Homo sapiens), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG2b Kappa
Citations	Sodium channel Na v 1.7 immunoreactivity in painful human dental pulp and burning mouth syndrome. Beneng K, et al. BMC Neurosci, 2010 Jun 8. PMID 20529324. Alternative splicing may contribute to time-dependent manifestation of inherited erythromelalgia. Choi JS, et al. Brain, 2010 Jun. PMID 20478850. Mutations at opposite ends of the DIII/S4-S5 linker of sodium channel Na V 1.7 produce distinct pain disorders. Cheng X, et al. Mol Pain, 2010 Apr 29. PMID 20429905. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614. Pain perception is altered by a nucleotide polymorphism in SCN9A. Reimann F, et al. Proc Natl Acad Sci U S A, 2010 Mar 16. PMID 20212137.
NCBI	NP_002968.1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Sodium channel protein type 9 subunit alpha,Neuroendocrine sodium channel,hNE-Na,Peripheral sodium channel 1,PN1,Sodium channel protein type IX subunit alpha,Voltage-gated sodium channel subunit alpha Nav17,SCN9A,NENA
Similar products	PN1, NENA, SCN9A, Sodium channel protein type 9 subunit alpha, Neuroendocrine sodium channel, Peripheral sodium channel 1, Sodium channel protein type IX subunit alpha, hNE-Na, Voltage-gated sodium channel subunit alpha Nav17
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Manufacturer - Targets	SCN9A (NP_002968, 269 a.a. ~ 339 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	This gene encodes a voltage-gated sodium channel which plays a significant role in nociception signaling. Mutations in this gene have been associated with primary erythermalgia, channelopathy-associated insensitivity to pain, and paroxysmal extreme pain disorder.
Clonality	Monoclonal
Gene Name	SCN9A
Subtitle	Mouse monoclonal antibody raised against a partial recombinant SCN9A.
Reactivity	H, Rat
Antigen Source	Human: ~~ Positive
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Concentration	1.0mg/ml
Dilution	WB: 1:500~1000 WB: 1:500~1000
Org Accession	NP_002968
Gene Description	sodium channel, voltage-gated, type IX, alpha subunit
Gene Summary	This gene encodes a voltage-gated sodium channel which plays a significant role in nociception signaling. Mutations in this gene have been associated with primary erythermalgia, channelopathy-associated insensitivity to pain, and paroxysmal extreme pain disorder. [provided by RefSeq
Antigen Type	Recombinant Protein

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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ABC-AT3795a-datasheet.pdf

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Menge: 100 ug

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