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SNCB Antibody (monoclonal) (M07)

ArtNr ABC-AT3979a
Hersteller Abcepta
Menge 100 ug
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB, ELISA
Clon 3H4
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG2a Kappa
Citations Association of alpha-, beta-, and gamma-Synuclein with diffuse lewy body disease. Nishioka K, et al. Arch Neurol, 2010 Aug. PMID 20697047.Expression of alpha-, beta- and gamma-synuclein in colorectal cancer, and potential clinical significance in progression of the disease. Ye Q, et al. Oncol Rep, 2010 Feb. PMID 20043104.Molecular determinants of the aggregation behavior of alpha- and beta-synuclein. Rivers RC, et al. Protein Sci, 2008 May. PMID 18436957.Spectroscopic and functional characterization of human beta-synuclein. Lee J, et al. Protein Pept Lett, 2007. PMID 18221001.An investigation into the lipid-binding properties of alpha-, beta- and gamma-synucleins in human brain and cerebrospinal fluid. Salem SA, et al. Brain Res, 2007 Sep 19. PMID 17692832.
NCBI NP_001001502.1,NP_003076.1
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Beta-synuclein,SNCB
Similar products SNCB, Beta-synuclein
Lieferbar
Manufacturer - Targets
SNCB (AAH02902, 1 a.a. ~ 134 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background
The protein encoded by this gene is highly homologous to alpha-synuclein. These proteins are abundantly expressed in the brain and putatively inhibit phospholipase D2 selectively. The encoded protein, which may play a role in neuronal plasticity, is abundant in neurofibrillary lesions of patients with Alzheimer disease. This protein has been shown to be highly expressed in the substantia nigra of the brain, a region of neuronal degeneration in patients with Parkinson disease; however, no direct relation to Parkinson disease has been established. Two transcript variants encoding the same protein have been found for this gene.
Clonality
Monoclonal
Gene Name
SNCB
Subtitle
Mouse monoclonal antibody raised against a full-length recombinant SNCB.
Reactivity
H
Antigen Source
Human: ~~ Positive
Formulation
Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution
WB: 1:500~1000
WB: 1:500~1000
E
Org Accession
AAH02902
Gene Description
synuclein, beta
Antigen Type
Recombinant Protein

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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