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STAT1 Antibody (monoclonal) (M01)

STAT1 Antibody (monoclonal) (M01)

ArtNr	ABC-AT4060a
Hersteller	Abcepta
Menge	100 ug
Kategorie	Oncology Neuroscience Targets for Rodent Neurosciences Antibodies By Cell Type Western Blot ELISA Immunofluorescence Primary Antibodies Immunostaining
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, IF, ELISA
Clon	1A8
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2a Kappa
Citations	Association of genetic polymorphisms in STAT1 gene with increased risk of hepatocellular carcinoma. Zhu ZZ, et al. Oncology, 2010. PMID 20798561.Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility hot-spot. Johnatty SE, et al. PLoS Genet, 2010 Jul 8. PMID 20628624.Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Dengue hemorrhagic fever is associated with polymorphisms in JAK1. Silva LK, et al. Eur J Hum Genet, 2010 Jun 30. PMID 20588308.Cooperative activation of CCL5 expression by TLR3 and tumor necrosis factor-alpha or interferon-gamma through nuclear factor-kappaB or STAT-1 in airway epithelial cells. Homma T, et al. Int Arch Allergy Immunol, 2010. PMID 20523058.
NCBI	NP_009330.1,NP_644671.1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Signal transducer and activator of transcription 1-alpha/beta,Transcription factor ISGF-3 components p91/p84,STAT1
Similar products	STAT1, Signal transducer and activator of transcription 1-alpha/beta, Transcription factor ISGF-3 components p91/p84
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Manufacturer - Targets	STAT1 (AAH02704, 613 a.a. ~ 712 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.
Clonality	Monoclonal
Gene Name	STAT1
Subtitle	Mouse monoclonal antibody raised against a partial recombinant STAT1.
Reactivity	H
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Concentration	1mg/ml
Dilution	IF WB: 1:500~1000 WB: 1:500~1000 E
Org Accession	AAH02704
Gene Description	signal transducer and activator of transcription 1, 91kDa
Gene Summary	The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq
Antigen Type	Recombinant Protein

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ABC-AT4060a-datasheet.pdf

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Menge: 100 ug

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Lieferung vsl. bis 01.01.2026

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