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TBX3 Antibody (monoclonal) (M02)

ArtNr ABC-AT4169a
Hersteller Abcepta
Menge 100 ug
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB, IF
Clon 8H3
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Mouse
Isotype IgG2a Kappa
Citations Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Recapitulation of two genomewide association studies on blood pressure and essential hypertension in the Korean population. Hong KW, et al. J Hum Genet, 2010 Jun. PMID 20414254.Development of the pacemaker tissues of the heart. Christoffels VM, et al. Circ Res, 2010 Feb 5. PMID 20133910.Genome-wide association study of PR interval. Pfeufer A, et al. Nat Genet, 2010 Feb. PMID 20062060.Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Talmud PJ, et al. Am J Hum Genet, 2009 Nov. PMID 19913121.
NCBI NP_005987.3,NP_057653.3
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias T-box transcription factor TBX3,T-box protein 3,TBX3
Similar products TBX3, T-box transcription factor TBX3, T-box protein 3
Lieferbar
Manufacturer - Targets
TBX3 (NP_005987, 311 a.a. ~ 410 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms; however, the full length nature of one variant has not been determined.
Clonality
Monoclonal
Gene Name
TBX3
Subtitle
Mouse monoclonal antibody raised against a partial recombinant TBX3.
Reactivity
H, M, Rat
Antigen Source
Human: ~~ Positive
Formulation
Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution
IF
WB: 1:500~1000
WB: 1:500~1000
WB: 1:500~1000
WB: 1:500~1000
Org Accession
NP_005987
Gene Description
T-box 3
Gene Summary
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms; however, the full length nature of one variant has not been determined. [provided by RefSeq
Antigen Type
Recombinant Protein

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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