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TRIP6 Antibody (monoclonal) (M04)

TRIP6 Antibody (monoclonal) (M04)

ArtNr	ABC-AT4364a
Hersteller	Abcepta
Menge	100 ug
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Applikationen	WB, IF, ELISA
Clon	4B7
Specific against	other
Host	Mouse
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	TRIP6, OIP1, Thyroid receptor-interacting protein 6, Opa-interacting protein 1, Zyxin-related protein 1, ZRP-1, OIP-1, TRIP-6, TR-interacting protein 6
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Primary Accession	Q15654
Antigen Type	Recombinant Protein
Application	WB, IF, E
Bio Background	This gene is a member of the zyxin family and encodes a protein with three LIM zinc-binding domains. This protein localizes to focal adhesion sites and along actin stress fibers. Recruitment of this protein to the plasma membrane occurs in a lysophosphatidic acid (LPA)-dependent manner and it regulates LPA-induced cell migration. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
Bio References	Lysophosphatidic acid 2 receptor-mediated supramolecular complex formation regulates its antiapoptotic effect. E S, et al. J Biol Chem, 2009 May 22. PMID 19293149.IL-12 stimulates the osteoclast inhibitory peptide-1 (OIP-1/hSca) gene expression in CD4+ T cells. Shanmugarajan S, et al. J Cell Biochem, 2009 May 1. PMID 19259951.An empirical framework for binary interactome mapping. Venkatesan K, et al. Nat Methods, 2009 Jan. PMID 19060904.TRIP6, a novel molecular partner of the MAGI-1 scaffolding molecule, promotes invasiveness. Chastre E, et al. FASEB J, 2009 Mar. PMID 19017743.Osteoclast inhibitory peptide-1 (OIP-1) inhibits measles virus nucleocapsid protein stimulated osteoclast formation/activity. Shanmugarajan S, et al. J Cell Biochem, 2008 Jul 1. PMID 18348201.
Clonality	Monoclonal
Gene ID	7205
Gene Name	TRIP6
Subtitle	Mouse monoclonal antibody raised against a partial recombinant TRIP6.
Reactivity	H
Legend image 1	Immunofluorescence of monoclonal antibody to TRIP6 on HeLa cell. [antibody concentration 35 ug/ml]
Type image 1	IF
Legend image 2	Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.52 KDa) .
Type image 2	WB
Dilution image 2	1:500~1000
Legend image 3	TRIP6 monoclonal antibody (M04), clone 4B7 Western Blot analysis of TRIP6 expression in Hela S3 NE ( (Cat # AT4364a )
Type image 3	WB
Dilution image 3	1:500~1000
Legend image 4	Western Blot analysis of TRIP6 expression in transfected 293T cell line by TRIP6 monoclonal antibody (M04), clone 4B7. Lane 1: TRIP6 transfected lysate(50.3 KDa). Lane 2: Non-transfected lysate.
Type image 4	WB
Dilution image 4	1:500~1000
Legend image 5	Detection limit for recombinant GST tagged TRIP6 is approximately 0.1ng/ml as a capture antibody.
Type image 5	E
Other Accession	NM_003302
Isotype	IgG3 Kappa
Antigen Source	Human: ~~ Positive
Target/Specificity	TRIP6 (NP_003293, 51 a.a. ~ 148 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
NCBI Accession	NP_003293.2
	Clone: 4B7
Org Accession	NP_003293
Gene Description	thyroid hormone receptor interactor 6
Gene Summary	This gene is a member of the zyxin family and encodes a protein with three LIM zinc-binding domains. This protein localizes to focal adhesion sites and along actin stress fibers. Recruitment of this protein to the plasma membrane occurs in a lysophosphatidic acid (LPA)-dependent manner and it regulates LPA-induced cell migration. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq

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Menge: 100 ug

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Lieferung vsl. bis 02.10.2025