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TXN Antibody (monoclonal) (M04)

TXN Antibody (monoclonal) (M04)

ArtNr	ABC-AT4415a
Hersteller	Abcepta
Menge	100 ug
Kategorie	Oncology Antibodies By Cell Type Carcinoma Cell Biology Cell Status Western Blot ELISA Immunofluorescence Senescence Primary Antibodies Immunostaining
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, IF, ELISA
Clon	6C10
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Citations	Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Thioredoxin-1 phosphorylated at T100 is needed for its anti-apoptotic activity in HepG2 cancer cells. Chen X, et al. Life Sci, 2010 Aug 14. PMID 20619274.Mammalian thioredoxin reductase 1: roles in redox homoeostasis and characterization of cellular targets. Turanov AA, et al. Biochem J, 2010 Sep 1. PMID 20536427.Common polymorphisms in ITGA2, PON1 and THBS2 are associated with coronary atherosclerosis in a candidate gene association study of the Chinese Han population. Wang Y, et al. J Hum Genet, 2010 Aug. PMID 20485444.Serum C-reactive protein and thioredoxin levels in subjects with mildly reduced glomerular filtration rate. Tsuchikura S, et al. BMC Nephrol, 2010 Apr 27. PMID 20423474.
NCBI	NP_001231867.1,NP_003320.2
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Thioredoxin,Trx,ATL-derived factor,ADF,Surface-associated sulphydryl protein,SASP,TXN,TRDX,TRX,TRX1
Similar products	TXN, TRX, SASP, TRX1, Thioredoxin, Trx, ADF, TRDX, ATL-derived factor, Surface-associated sulphydryl protein
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Manufacturer - Targets	TXN (AAH03377, 1 a.a. ~ 105 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	Thioredoxin is a 12-kD oxidoreductase enzyme containing a dithiol-disulfide active site. It is ubiquitous and found in many organisms from plants and bacteria to mammals. Multiple in vitro substrates for thioredoxin have been identified, including ribonuclease, choriogonadotropins, coagulation factors, glucocorticoid receptor, and insulin. Reduction of insulin is classically used as an activity test.
Clonality	Monoclonal
Gene Name	TXN
Subtitle	Mouse monoclonal antibody raised against a partial recombinant TXN.
Reactivity	H
Antigen Source	Human: ~~ Positive
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution	IF WB: 1:500~1000 WB: 1:500~1000 E
Org Accession	AAH03377
Gene Description	thioredoxin
Gene Summary	Thioredoxin is a 12-kD oxidoreductase enzyme containing a dithiol-disulfide active site. It is ubiquitous and found in many organisms from plants and bacteria to mammals. Multiple in vitro substrates for thioredoxin have been identified, including ribonuclease, choriogonadotropins, coagulation factors, glucocorticoid receptor, and insulin. Reduction of insulin is classically used as an activity test.[supplied by OMIM
Antigen Type	Recombinant Protein

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ABC-AT4415a-datasheet.pdf

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Menge: 100 ug

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Lieferung vsl. bis 01.01.2026

Express-Lieferung: 27 Tage sparen

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