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VCP Antibody (monoclonal) (M03)

VCP Antibody (monoclonal) (M03)

ArtNr	ABC-AT4506a
Hersteller	Abcepta
Menge	100 ug
Kategorie	Neuroscience Molecular Targets for Neuroscience Antibodies Immunohistochemistry Western Blot ELISA Primary Antibodies Immunostaining
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, IHC, ELISA
Clon	4A8
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG2a Kappa
Citations	Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.A novel ATP-dependent conformation in p97 N-D1 fragment revealed by crystal structures of disease-related mutants. Tang WK, et al. EMBO J, 2010 Jul 7. PMID 20512113.Centrosome-related genes, genetic variation, and risk of breast cancer. Olson JE, et al. Breast Cancer Res Treat, 2010 May 28. PMID 20508983.Identification of Caspase-6-mediated processing of the valosin containing protein (p97) in Alzheimer's disease: a novel link to dysfunction in ubiquitin proteasome system-mediated protein degradation. Halawani D, et al. J Neurosci, 2010 Apr 28. PMID 20427671.Imbalances in p97 co-factor interactions in human proteinopathy. Fern?ndez-S?iz V, et al. EMBO Rep, 2010 Jun. PMID 20414249.
NCBI	NP_009057.1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Transitional endoplasmic reticulum ATPase,TER ATPase,15S Mg(2+)-ATPase p97 subunit,Valosin-containing protein,VCP,VCP
Similar products	VCP, TER ATPase, Transitional endoplasmic reticulum ATPase, 15S Mg(2+)-ATPase p97 subunit, Valosin-containing protein
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Manufacturer - Targets	VCP (AAH07562, 1 a.a. ~ 588 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background	The protein encoded by this gene is a member of a family that includes putative ATP-binding proteins involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. This protein, as a structural protein, is associated with clathrin, and heat-shock protein Hsc70, to form a complex. It has been implicated in a number of cellular events that are regulated during mitosis, including homotypic membrane fusion, spindle pole body function, and ubiquitin-dependent protein degradation.
Clonality	Monoclonal
Gene Name	VCP
Subtitle	Mouse monoclonal antibody raised against a full-length recombinant VCP.
Reactivity	H, M, Rat
Antigen Source	Human: ~~ Positive
Formulation	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution	WB: 1:500~1000 WB: 1:500~1000 WB: 1:500~1000 WB: 1:500~1000 IHC
Org Accession	AAH07562
Gene Description	valosin-containing protein
Gene Summary	The protein encoded by this gene is a member of a family that includes putative ATP-binding proteins involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. This protein, as a structural protein, is associated with clathrin, and heat-shock protein Hsc70, to form a complex. It has been implicated in a number of cellular events that are regulated during mitosis, including homotypic membrane fusion, spindle pole body function, and ubiquitin-dependent protein degradation. [provided by RefSeq
Antigen Type	Recombinant Protein

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ABC-AT4506a-datasheet.pdf

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Menge: 100 ug

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Lieferung vsl. bis 01.01.2026

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