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VIL2 Antibody (monoclonal) (M04)

ArtNr ABC-AT4512a
Hersteller Abcepta
Menge 100 ug
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB, IHC, ELISA
Clon 100000000000
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG2b Kappa
Citations Ezrin immunoreactivity in renal cell carcinomas. Tuna B, et al. Anal Quant Cytol Histol, 2009 Oct. PMID 20701102.Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility hot-spot. Johnatty SE, et al. PLoS Genet, 2010 Jul 8. PMID 20628624.Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Immunoexpression of Ezrin and CD44 in patients with osteosarcoma. Boldrini E, et al. J Pediatr Hematol Oncol, 2010 Aug. PMID 20562647.Ezrin immunohistochemical expression in chondrosarcomas, osteosarcomas and Ewing sarcoma family of tumors. Machado I, et al. Virchows Arch, 2010 Jul. PMID 20552365.
NCBI NP_001104547.1,NP_003370.2
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Ezrin,Cytovillin,Villin-2,p81,EZR,VIL2
Similar products Ezrin, VIL2, EZR, Cytovillin, Villin-2, p81
Lieferbar
Manufacturer - Targets
EZR (AAH13903, 1 a.a. ~ 586 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Bio Background
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.
Clonality
Monoclonal
Gene Name
EZR
Subtitle
Mouse monoclonal antibody raised against a full-length recombinant VIL2.
Reactivity
H
Antigen Source
Human: ~~ Positive
Formulation
Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Dilution
WB: 1:500~1000
WB: 1:500~1000
IHC
E
Org Accession
AAH13903
Gene Description
ezrin
Gene Summary
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. [provided by RefSeq
Antigen Type
Recombinant Protein

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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