Phospho-SHP2(Y546) Antibody

Primary Antibodies; Antibody Collections; Phospho Antibodies; Interferon-gamma signaling; Jak-STAT signaling KEGG

SHP2 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration.

PTPN11

H, M

68011

521-551

WB: 1:1000
WB: 1:1000
DB: 1:500