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EGFR Antibody

ArtNr ABC-AW5392-U100
Hersteller Abcepta
Menge 100 ul
Kategorie
Typ Antibody Primary
Applikationen WB, FC, IHC
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG1 Kappa
Citations Complex Mutations in the Epidermal Growth Factor Receptor Gene in Non-small Cell Lung Cancer. Hata A, et al. J Thorac Oncol, 2010 Aug 30. PMID 20808254. EGFR signaling is differentially activated in patient-derived glioblastoma stem cells. Howard BM, et al. J Exp Ther Oncol, 2010. PMID 20734923. [EGFR Mutations Detection in Non-small Cell Lung Cancer Tissues by Real-time PCR and DNA Sequencing.] Li Y, et al. Zhongguo Fei Ai Za Zhi, 2009 Dec 20. PMID 20723379. [Detection and Its Clinical Significance of EGFR Gene Mutation and Gene Amplification in 187 Patients with Non-small Cell Lung Cancer.] Liu H, et al. Zhongguo Fei Ai Za Zhi, 2009 Dec 20. PMID 20723374. Effect of gefitinib on the survival of patients with recurrence of lung adenocarcinoma after surgery: A retrospective case-matching cohort study. Katayama T, et al. Surg Oncol, 2010 Aug 10. PMID 20705455.
NCBI NP_005219.2,NP_958439.1,NP_958440.1,NP_958441.1
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Epidermal growth factor receptor,Proto-oncogene c-ErbB-1,Receptor tyrosine-protein kinase erbB-1,EGFR,ERBB,ERBB1,HER1
Similar products EGFR, ERBB, ERBB1, HER1, Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1
Lieferbar
Manufacturer - Category
Primary Antibodies; Anti-Kinome Antibodies
Manufacturer - Targets
Purified His-tagged EGFR protein(Fragment) was used to produced this monoclonal antibody.
Bio Background
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.
Clonality
Monoclonal
Gene Name
EGFR
Subtitle
Purified Mouse Monoclonal Antibody (Mab)
Reactivity
H
Calculated Molecular Weight
134277
Antigen Source
HUMAN
Antigen Region
49-299
Formulation
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Dilution
WB: 1:1000
IHC: 1:25
IHC: 1:25
FC: 1:25
Antigen Type
Recombinant Protein

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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