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Phospho BCL-XL [Thr115]

Phospho BCL-XL [Thr115]

ArtNr	ANOG-AI70003D-0.5mg
Hersteller	Anogen
Menge	0.5mg
Kategorie	Oncology Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Cell Biology Cell Status Apoptosis ELISA Primary Antibodies By Organ Colorectal Cancer Testicular & Prostate Cancer
Typ	Antibody Polyclonal
Format	Purified
Applikationen	ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Protein Familie	Signal Transduction
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	BCL-XL
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Description	Rabbit anti-Threonine 115 phosphorylated Bcl-xL polyclonal antibody
Target Protein	Threonine 115 phosphorylated Bcl-xL.
Immunogen	A synthetic peptide (TSQLHITpPGTAY) derived from Threonine 115 phosphorylated Bcl-xL, conjugated with KLH for immunization
Specificity	This antibody is reactive to the synthetic Bcl-xL peptide (TSQLHITpPGTAY).
Purification	Protein G affinity purified
Species Reactivity	Human and other species with consensus Bcl-xL peptide (TSQLHITpPGTAY)
Background	Bcl-xL is a prosurvival factor in the Bcl-2 family. It is a mitochondrial outer membrane protein that regulates the voltage-dependent anion channels (VDAC), and controls the production of reactive oxygen species and the release of cytochrome C. Bcl-xL gene knock-out resulted in embryonic lethality in animal model due to neuronal apoptosis and erythroid apoptosis. Bcl-xL is believed to be involved with the survival and differentiation of erythroid cells, iron metabolism and hemoglobin synthesis.
Formulation	Lyophilized in pH 7.4, 0.01M PBS.
Reconstitution	Double distilled water is recommended to adjust the final concentration to 1.00mg/mL.
Application info	ELISA: The antibody, when 1:10, 000 - 1:100, 000 diluted, can detect the Threonine 115 phosphorylated Bcl-xL coated on ELISA plate. Other applications have not been evaluated.
Research Area	Life science research, apoptotic signalling
Storage	Store at -20C

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Menge: 0.5mg

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Lieferung vsl. bis 20.11.2025