Phospho NF-kB-p65 [Ser276]

Rabbit anti-Serine276 phosphorylated NF-kB p65 polyclonal antibody

A synthetic peptide (QLRRPSpDRELS) derived from Serine 276 phosphorylated NF-kB p65, conjugated with KLH for immunization.

Protein G affinity purified

NF-kB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a transcription factor that controls the transcription of many genes that are associated with immuno-response, anti-apoptosis, neuroplasticity and memory. There are five NF-kB proteins in mammals: RelA(NF-kB p65), RelB, c-Rel, NF-kB (NF-kB p105), and NF-kB2 (NF-kB p100). They form a variety of homodimers and heterodimers, each of which activates its own distinctive set of genes. P65 has been shown to be involved with DNA binding. Mitogen and stress activated protein kinase phosphorylates NF-kB p65 at serine 276 and controls stem cell factor expression in inflammation.

Double distilled water is recommended to adjust the final concentration to 1.00mg/mL.

Life science research, stem cell factor signalling, cancer research