Monocyte Chemotactic Protein-1 (MCP-1/ MCAF) (**Biotin Labeled)

Biotin conjugated mouse monoclonal antibody to human Monocyte Chemotactic Protein-1 (MCP-1)/ Monocyte Chemotactic and Activating Factor (MCAF)

Purified recombinant human MCP-1

Protein G affinity purified

This antibody does not react with human interleukin-8 (IL-8) and other human cytokines tested such as interleukin-1beta (IL-1beta), serum amyloid A (SAA) and epidermal growth factor (EGF).

Monocyte chemotactic and activating factor (MCAF) is also called monocyte chemotactic protein-1 (MCP-1) and chemokine (C-C motif) ligand 2 (CCL2). It is primarily secreted by monocytes, macrophages and dendritic cells. This cytokine displays chemotactic activity for monocytes, T-cells, and basophils, but not for neutrophils or eosinophils. MCAF causes the degranulation of basophils and mast cells, and augments the activity of monocyte and macrophage. MCAF plays an important role in inflammation, angiogenesis, auto-immune diseases, renal diseases, chronic infection and granuloma formation.

ELISA: In combination with capture antibody S14 (Cat. No.: MO-C40021B) and avidin-HRP conjugate, this biotin conjugated antibody can be used as tracer for detection of human MCP-1 in sandwich ELISA.

Store at -20C