Epidermal Growth Factor (EGF)

Mouse monoclonal antibody to human epidermal growth factor (EGF)

Purified recombinant human EGF, 6kDa, 53 amino acid residues

Protein G affinity purified

Does not cross react with other human cytokines tested such as IL-1beta, IL-8, MCAF, TGF-beta and SAA.

Epidermal growth factor (EGF), along with its receptor EGFR, plays an important role in cell proliferation, differentiation and survival. The binding of EGF to EGFR triggers the intrinsic tyrosine kinase activity of EGFR, activates signalling molecules and stimulates the synthesis of proteins and DNAs.
EGF is crucial for maintaining mucosal lining in gastrointestinal duct and for healing of oral and gastro esophageal ulcers. EGF signalling is needed for cancer growth. Monoclonal antibodies that block EGFR have been applied for lung cancer and colon inhibition.

Double distilled water is recommended to adjust the final concentration to 1.00mg/mL.

Growth Factor and Cytokine