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Macrophage/Monocyte Chemotactic Protein (MCP-3)

Macrophage/Monocyte Chemotactic Protein (MCP-3)

ArtNr	ANOG-MO-C40088B
Hersteller	Anogen
Menge	0.5mg
Kategorie	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Antibodies Western Blot Primary Antibodies By Organ Heart & Blood Cancer
Typ	Antibody Monoclonal
Format	Aff. Pur
Applikationen	WB
Clon	343
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 kappa
Protein Familie	Cytokine, Growth Factors
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Similar products	MCP-3
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Description	Mouse monoclonal antibody to human macrophage/monocyte chemotactic protein-3 (MCP-3)
Target Protein	Human MCP-3
Immunogen	Recombinant human MCP-3 (M.W. 8.5kDa containing 76 amino acids residues)
Specificity	Reactive with natural and recombinant human MCP-3
Purification	Protein G affinity purified
Species Reactivity	Human, other species not tested
Cross Reactivity	Does not show any cross reaction with other human cytokines or growth factors tested such as IL-1beta, IL-8, MCAF, SAA and EGF.
Myeloma	Sp2/0-Ag14
Background	Macrophage/monocyte chemotactic protein-3 (MCP-3), like other two closely related chemokines (MCP1 and MCP-2), is chemotactic to monocytes, but not to neutrophils. MCP-3 showed 78% sequence homology with MCP-1 and 58% sequence homology with MCP-2. The primary receptor for MCP-3 is D6. MCP-3 also competes with MCP-1 to bind to CCR10, and competes with Rantes and MIP-1alpha to bind to CCR1. MCP-3 stimulates macrophage to secrete proteases. A variety of cancer cell lines express MCP-3, suggesting a role in tumor invasion and metastasia.
Formulation	Lyophilized from a solution in 0.01M PBS, pH 7.2.
Reconstitution	Double distillated water is recommended to reconstitute the antibody.
Application info	Western Blot: This antibody, when used at concentration of 1-4ug/mL will allow visualization of 0.1ug/lane of human MCP-3.
Research Area	Cytokine, chemotaxis.
Storage	Store at -20C

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Menge: 0.5mg

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Lieferung vsl. bis 20.11.2025