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Beta amyloid peptide N-terminal

ArtNr ANOG-MO-M40094I
Hersteller Anogen
Menge 0.5mg
Kategorie
Typ Antibody Monoclonal
Format Aff. Pur
Applikationen IHC
Clon NT 7G10
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG2b kappa
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Lieferbar
Description
Mouse monoclonal antibody against N-terminal sequence of human amyloid beta peptides
Target Protein
Human beta amyloid peptide 45
Immunogen
Full length human beta amyloid peptide 45
Specificity
This antibody recognizes the N-terminal peptide (DAEFRHDS) of human beta amyloid peptides and also reacts with full length Abeta40, Abeta42 and Abeta43.
Purification
Protein G affinity purified
Species Reactivity
Human
Myeloma
Sp2/0-Ag14
Background
Abeta40, Abeta42 and Abeta43 are different only at the few C-end amino acids. While the C-end amino acids showed no species-specificity in mammalians, the N-terminal amino acid sequences have minor discrepancies between difference species.
Amyloid beta peptides Abeta42 and Abeta40 have been investigated extensively for predicating Alzheimer’s disease. A recent study on A Abeta43 in brain showed that Abeta43 is more fibrillogenic than the other amyloid beta peptides and may be useful as a biomarker or therapeutic target for Alzheimer’s disease. Antibody to N-terminal sequence can bind to all the three amyloid beta peptides.
Formulation
Lyophilized from a solution in 0.01M PBS pH7.2
Reconstitution
Double distilled water is recommended to adjust the final concentration to 1.00 mg/mL.
Application info
ELISA: The antibody can be used as capture antibody in Sandwich ELISA for Abeta42 detection in combination with detection antibody CA9 10C11 (Cat. No.: MO-M40093B)
The antibody can be used as capture antibody in Sandwich ELISA for Abeta40 detection in combination with detection antibody CV9 7B11 (Cat. No.: MO-M40095A).
Research Area
Aging and neurodegenerative diseases
Storage
Store at -20C

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.5mg
Lieferbar: In stock
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Lieferung vsl. bis 20.11.2025 

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