STAT5b [p-T694]

ArtNr	ANOG-MO-P40001B
Hersteller	Anogen
Menge	0.5mg
Kategorie	Oncology Antibodies By Cell Type Hematology Leukemia Lymphoma ELISA Primary Antibodies By Organ Heart & Blood Cancer
Typ	Antibody Monoclonal
Format	Aff. Pur
Applikationen	ELISA
Clon	A2H6
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2b kappa
Protein Familie	Signal Transduction
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Similar products	STAT5b
Lieferbar
Description	Mouse monoclonal antibody against tyrosine 699 phosphorylated human signal transducer and activator of transcription 5b (p-STAT5b).
Target Protein	Tyrosine 699 phosphorylated human STAT5b
Immunogen	A tyrosine 699 phosphorylated human STAT5b peptide fragment conjugated with KLH.
Specificity	Reactive to tyrosine 699 phosphorlylated human STAT5b peptide fragment conjugated with KLH or the peptide-BSA conjugate, but not reactive to un-conjugated KLH or BSA?
Purification	Protein G affinity purified
Species Reactivity	Human, others not tested
Myeloma	Sp2/0-Ag14
Background	Stat5b is a transcription factor that is activated in response to extra-cellular stimuli including IL-2, IL-4, MCSF and a variety of growth factors. In the process, receptor associated kinases phosphorylate Stat5b. Stat5b, then, forms dimers and translocates to nucleus. Inside nucleus, Stat5b binds to the promoter region on various genes to regulate biological processes such as apoptosis, T cell receptor signalling, and adult mammary gland development. Fusion of Stat5b to retinoic acid receptor-alpha (RARalpha) gene was identified in a small subgroup of acute promyelocytic leukemia patients.
Formulation	Lyophilized form from a solution of 0.01M PBS, pH7.0
Reconstitution	Double distilled water is recommended to adjust the final concentration to 1.00mg/mL.
Application info	In indirect ELISA, the antibody is reactive to tyrosine699 phosphorlylated human STAT5b peptide fragment conjugated with KLH or the peptide-BSA conjugate. The conjugates were coated to ELISA plate at 1ug/ml in pH 9.5 carbonate buffer. Other applications have not been evaluated.
Research Area	Signal transduction, gene transcription
Storage	Store at -20C

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

Produkt-Datenblatt anfordern

Sicherheitsdatenblatt anfordern

Einfache Bestellung Periodische Bestellung

Menge: 0.5mg

lieferbar

Lieferung vsl. bis 18.12.2025

Express-Lieferung: 27 Tage sparen

Vergleichen

Auf den Wunschzettel

Angebot anfordern