Alpha Fetoprotein

Mouse monoclonal antibody to human alpha fetoprotein (AFP)

Human AFP, which was isolated from amniotic fluid and purified by affinity chromatography.

Protein G affinity purified

No detectable cross-reaction with human normal serum proteins.

Alpha fetoprotein (AFP) is a 70kD glycoprotein which is produced primarily by liver cells in foetuses. It exists in significant amount in foetal plasma and decreases rapidly after birth. Moderate amount of AFP exists in serum of pregnant women. Monitoring mother’s serum AFP level in second trimester pregnancy can help assessing birth defects such as Down syndrome, neural tube defect and anencephaly. Elevated AFP level in men, children and non-pregnant women is associated with neoplastic conditions in lever, testicle or ovary.

Double distilled water is recommended to adjust the final concentration to 1.00mg/mL.

Oncology