Anti-MHC Class II DQ DR Polymorphic Antibody [49.1]

MHC Class II DQ DR Polymorphic

Mouse monoclonal [49.1] antibody to MHC Class II DQ DR Polymorphic (FITC).

100 µg/ml

Protein A affinity chromatography of tissue culture supernatant.

This antibody recognises a polymorphic epitope on ovine MHC class II DQ and DR molecules, constitutively expressed on antigen presenting cells including dendritic cells, B lymphocytes, monocytes, macrophages, activated T lymphocytes and may be induced on a range of other cell types by interferon gamma.The major histocompatibility complex (MHC) is a cluster of genes some of which are important in the immune response to infection. In sheep, this complex is referred to as the ovine leukocyte antigen (OLA) region. There are 2 major types of MHC class IIa molecules encoded by the OLA which are DR and DQ each composed of an alpha and beta chain.recognises ovine MHC II transfectants DQ - T28.1, DQ - T26.2 and DR - T31.3 but not DR - T8.1.