Anti-TIMP-1 Antibody

ArtNr	ANTI-A283297-100
Hersteller	Antibodies.com
Menge	100 ug
Kategorie	Antibodies Immunohistochemistry Western Blot ELISA Primary Antibodies Immunostaining Functional Assays
Typ	Antibody Primary
Format	Lyophilized
Applikationen	WB, ELISA, IHC-P, FA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Lieferbar
Storage Conditions	Lyophilized: Store at -20°C. Reconstituted: Store undiluted at -20°C, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.
Product Description	Rabbit polyclonal antibody to TIMP1.
Clonality	Polyclonal
Immunogen	Recombinant human TIMP-1.
Concentration	1 mg/ml after reconstitution.
Manufacturer - Formulation	Supplied in Phosphate Buffered Saline.
Recommended dilutions	ELISA: 0.5 - 2 µg/ml, WB: 0.1 - 0.2 µg/ml
Manufacturer - Specificity	This antibody recognises human TIMP-1 (Tissue Inhibitor of Metalloproteinase -1), a secreted glycoprotein and member of the protease inhibitor I35 (TIMP) family, which is expressed by a wide range of cells, including microvascular endothelial cells, smooth muscle cells, mesangial cells, and some fibroblasts. TIMP-1 acts as a natural extracellular inhibitor of MMPs (matrix metalloproteinases), a group of peptidases involved in degradation of the extracellular matrix, and is also involved in erythropoiesis, through the simulation of the proliferation/differentiation of erythroid progenitors. A correlation between localized concentrations of TIMP-1 and TIMP-3, may determine cell fate, and that increased expression of TIMP-1, may act as an inhibitor/suppressor of invasive cell growth
Reconstitution	Reconstitute with 0.1 ml of distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Gently mix after reconstitution. For long term storage the addition of 0.09% sodium azide is recommended.

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Menge: 100 ug

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Lieferung vsl. bis 13.11.2025

Express-Lieferung: 3 Tage sparen

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