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Anti-MDC Antibody Europäischer Partner

ArtNr ANTI-A283931-100
Hersteller Antibodies.com
Menge 100 ug
Kategorie
Typ Antibody Primary
Format Lyophilized
Applikationen WB, ELISA, FA
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Lieferbar
Manufacturer - Targets
MDC
Storage Conditions
Lyophilized: Store at -20°C. Reconstituted: Store undiluted at -20°C, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.
Product Description
Rabbit polyclonal antibody to MDC.
Clonality
Polyclonal
Immunogen
Recombinant human MDC.
Concentration
1 mg/ml after reconstitution.
Manufacturer - Formulation
Supplied in Phosphate Buffered Saline.
Recommended dilutions
ELISA: 0.5 µg/ml, Functional Assays: 5.0 - 7.0 µg/ml, WB: 0.1 - 0.2 µg/ml
Manufacturer - Specificity
This antibody recognises human MDC, also known as macrophage-derived cytokine, CCL22, CC chemokine STCP-1, Small-inducible cytokine A22 or Stimulated T-cell chemotactic protein 1. MDC is a 93 amino acid, ~10.6 kDa member of the CC chemokine family expressed by macrophages, monocyte-derived dendritic cells, epithelial cells, fibroblasts and highly expressed in the thymus. MDC acts as a chemoattractant for monocytes, dendritic cells, activated T lymphocytes and NK cells, through binding to chemokine (C-C motif) receptor 4 (CCR4). CCR4 is selectively expressed by Th2 cells is linked to another ligand of CCR4, known as activation-regulated chemokine (TARC/CCL17), with Th2-mediated inflammatory disorders such as atopic dermatitis and ulcerative colitis.
Reconstitution
Reconstitute with 0.1 ml of distilled water. For long term storage the addition of 0.09% sodium azide is recommended. For functional studies do not add sodium azide.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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